GO Annotations Graph

• Symbol: Dmd
• Name: dystrophin, muscular dystrophy
• ID: MGI:94909

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:155856
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0002162	dystroglycan binding	ISO	J:164563
Molecular Function	GO:0005178	integrin binding	ISO	J:155856
Molecular Function	GO:0005521	lamin binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0017022	myosin binding	ISO	J:164563
Molecular Function	GO:0050998	nitric-oxide synthase binding	IPI	J:139346
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:184033
Molecular Function	GO:0005515	protein binding	IPI	J:119852
Molecular Function	GO:0005515	protein binding	IPI	J:41623
Molecular Function	GO:0005515	protein binding	IPI	J:263460
Molecular Function	GO:0005515	protein binding	IPI	J:249197
Molecular Function	GO:0005515	protein binding	IPI	J:134710
Molecular Function	GO:0005515	protein binding	IPI	J:111508
Molecular Function	GO:0005515	protein binding	IPI	J:80393
Molecular Function	GO:0005515	protein binding	IPI	J:80393
Molecular Function	GO:0005515	protein binding	IPI	J:135327
Molecular Function	GO:0005515	protein binding	IPI	J:125409
Molecular Function	GO:0005515	protein binding	IPI	J:125409
Molecular Function	GO:0005515	protein binding	IPI	J:33699
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0008307	structural constituent of muscle	ISO	J:164563
Molecular Function	GO:0017166	vinculin binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0097449	astrocyte projection	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030054	cell junction	IDA	J:220106
Cellular Component	GO:0042995	cell projection	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0030055	cell-substrate junction	IDA	J:125409
Cellular Component	GO:0043034	costamere	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0016010	dystrophin-associated glycoprotein complex	ISO	J:155856
Cellular Component	GO:0016010	dystrophin-associated glycoprotein complex	ISO	J:164563
Cellular Component	GO:0016010	dystrophin-associated glycoprotein complex	IDA	J:125409
Cellular Component	GO:0030175	filopodium	ISO	J:164563
Cellular Component	GO:0031527	filopodium membrane	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	ISO	J:155856
Cellular Component	GO:0099617	matrix side of mitochondrial inner membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0045121	membrane raft	IDA	J:69965
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:155856
Cellular Component	GO:0030016	myofibril	ISO	J:155856
Cellular Component	GO:0005883	neurofilament	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0044306	neuron projection terminus	IDA	J:77234
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:117855
Cellular Component	GO:0005886	plasma membrane	IDA	J:87935
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IEA	J:60000
Cellular Component	GO:0099572	postsynaptic specialization	IDA	J:326667
Cellular Component	GO:0099572	postsynaptic specialization	IDA	J:326667
Cellular Component	GO:0032991	protein-containing complex	ISO	J:138112
Cellular Component	GO:0005840	ribosome	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	ISO	J:164563
Cellular Component	GO:0042383	sarcolemma	IBA	J:265628
Cellular Component	GO:0042383	sarcolemma	IDA	J:113292
Cellular Component	GO:0042383	sarcolemma	IDA	J:125409
Cellular Component	GO:0042383	sarcolemma	IDA	J:69965
Cellular Component	GO:0042383	sarcolemma	IDA	J:108320
Cellular Component	GO:0042383	sarcolemma	IDA	J:66558
Cellular Component	GO:0042383	sarcolemma	IDA	J:33699
Cellular Component	GO:0030141	secretory granule	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:76455
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0030018	Z disc	IDA	J:125409
Biological Process	GO:0060348	bone development	IGI	J:201690
Biological Process	GO:0086001	cardiac muscle cell action potential	IMP	J:156537
Biological Process	GO:0086001	cardiac muscle cell action potential	IMP	J:196253
Biological Process	GO:0060048	cardiac muscle contraction	ISO	J:164563
Biological Process	GO:0061448	connective tissue development	IGI	J:201690
Biological Process	GO:0008340	determination of adult lifespan	IGI	J:201690
Biological Process	GO:0008065	establishment of blood-nerve barrier	IMP	J:104866
Biological Process	GO:0060857	establishment of glial blood-brain barrier	IMP	J:104866
Biological Process	GO:0010467	gene expression	IGI	J:201690
Biological Process	GO:0010467	gene expression	IMP	J:211088
Biological Process	GO:0060173	limb development	IGI	J:201690
Biological Process	GO:0035264	multicellular organism growth	IGI	J:201690
Biological Process	GO:0032504	multicellular organism reproduction	IGI	J:201690
Biological Process	GO:0046716	muscle cell cellular homeostasis	IMP	J:7361
Biological Process	GO:0046716	muscle cell cellular homeostasis	IMP	J:7361
Biological Process	GO:0055001	muscle cell development	IBA	J:265628
Biological Process	GO:0055001	muscle cell development	IGI	J:28545
Biological Process	GO:0007517	muscle organ development	IMP	J:87688
Biological Process	GO:0014904	myotube cell development	IMP	J:150127
Biological Process	GO:0014904	myotube cell development	IMP	J:150127
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	IMP	J:87819
Biological Process	GO:0045665	negative regulation of neuron differentiation	ISO	J:155856
Biological Process	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation	IMP	J:146474
Biological Process	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation	IMP	J:156537
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	IMP	J:196427
Biological Process	GO:0048666	neuron development	IBA	J:265628
Biological Process	GO:0048812	neuron projection morphogenesis	ISO	J:155856
Biological Process	GO:0045213	neurotransmitter receptor metabolic process	IMP	J:43694
Biological Process	GO:0051647	nucleus localization	IMP	J:150127
Biological Process	GO:0021629	olfactory nerve structural organization	IMP	J:138609
Biological Process	GO:0043043	peptide biosynthetic process	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	IMP	J:196120
Biological Process	GO:0045666	positive regulation of neuron differentiation	ISO	J:155856
Biological Process	GO:0045666	positive regulation of neuron differentiation	ISO	J:164563
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:164563
Biological Process	GO:2000651	positive regulation of sodium ion transmembrane transporter activity	IMP	J:196253
Biological Process	GO:0008104	protein localization	ISO	J:164563
Biological Process	GO:0008104	protein localization	IMP	J:139346
Biological Process	GO:0065003	protein-containing complex assembly	IMP	J:156537
Biological Process	GO:0065003	protein-containing complex assembly	IMP	J:146474
Biological Process	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	IMP	J:156537
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:155856
Biological Process	GO:0090287	regulation of cellular response to growth factor stimulus	ISO	J:164563
Biological Process	GO:0090287	regulation of cellular response to growth factor stimulus	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:19383
Biological Process	GO:0010468	regulation of gene expression	IMP	J:177504
Biological Process	GO:0002027	regulation of heart rate	ISO	J:164563
Biological Process	GO:0002027	regulation of heart rate	IMP	J:156537
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:105953
Biological Process	GO:0090257	regulation of muscle system process	IBA	J:265628
Biological Process	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	IMP	J:196427
Biological Process	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	IMP	J:156537
Biological Process	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	IMP	J:156537
Biological Process	GO:0014819	regulation of skeletal muscle contraction	IMP	J:146474
Biological Process	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	IMP	J:146474
Biological Process	GO:1901385	regulation of voltage-gated calcium channel activity	IMP	J:196253
Biological Process	GO:0035994	response to muscle stretch	IMP	J:87819
Biological Process	GO:0035994	response to muscle stretch	IMP	J:105953
Biological Process	GO:0007519	skeletal muscle tissue development	IBA	J:265628
Biological Process	GO:0007519	skeletal muscle tissue development	IMP	J:108320
Biological Process	GO:0007519	skeletal muscle tissue development	IGI	J:100052
Biological Process	GO:0055002	striated muscle cell development	IGI	J:201690
Biological Process	GO:0006941	striated muscle contraction	IGI	J:201690
Biological Process	GO:0099536	synaptic signaling	IBA	J:265628
Biological Process	GO:0090659	walking behavior	IGI	J:201690