GO Annotations Graph

• Symbol: Drd5
• Name: dopamine receptor D5
• ID: MGI:94927

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035240	dopamine binding	ISO	J:164563
Molecular Function	GO:0004952	dopamine neurotransmitter receptor activity	ISO	J:155856
Molecular Function	GO:0004952	dopamine neurotransmitter receptor activity	ISO	J:164563
Molecular Function	GO:0004952	dopamine neurotransmitter receptor activity	ISO	J:73065
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IBA	J:265628
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IDA	J:114543
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IDA	J:114543
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IMP	J:100026
Molecular Function	GO:0004930	G protein-coupled receptor activity	IBA	J:265628
Molecular Function	GO:0001965	G-protein alpha-subunit binding	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0031526	brush border membrane	ISO	J:155856
Cellular Component	GO:0031526	brush border membrane	IDA	J:95570
Cellular Component	GO:0060170	ciliary membrane	ISO	J:164563
Cellular Component	GO:0005929	cilium	ISO	J:246963
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0097730	non-motile cilium	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Biological Process	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:73065
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA	J:95570
Biological Process	GO:0008306	associative learning	IMP	J:114239
Biological Process	GO:0071870	cellular response to catecholamine stimulus	ISO	J:164563
Biological Process	GO:0007212	dopamine receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007212	dopamine receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0060292	long-term synaptic depression	IMP	J:100026
Biological Process	GO:0007617	mating behavior	IMP	J:114239
Biological Process	GO:0045776	negative regulation of blood pressure	IGI	J:95908
Biological Process	GO:0045776	negative regulation of blood pressure	IMP	J:95570
Biological Process	GO:0045776	negative regulation of blood pressure	IMP	J:95908
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:155856
Biological Process	GO:0033861	negative regulation of NAD(P)H oxidase activity	ISO	J:164563
Biological Process	GO:0006469	negative regulation of protein kinase activity	ISO	J:155856
Biological Process	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	IMP	J:95908
Biological Process	GO:0072593	reactive oxygen species metabolic process	ISO	J:164563
Biological Process	GO:0045924	regulation of female receptivity	IMP	J:114239
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	ISO	J:155856
Biological Process	GO:0001992	regulation of systemic arterial blood pressure by vasopressin	IGI	J:95908
Biological Process	GO:0001992	regulation of systemic arterial blood pressure by vasopressin	IGI	J:95908
Biological Process	GO:0001975	response to amphetamine	IGI	J:103950
Biological Process	GO:0042220	response to cocaine	IMP	J:103887
Biological Process	GO:0046960	sensitization	IGI	J:103950
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0019226	transmission of nerve impulse	IMP	J:84475
Biological Process	GO:0008542	visual learning	ISO	J:155856
Biological Process	GO:0042060	wound healing	IMP	J:111218