GO Annotations Graph

• Symbol: Ect2
• Name: ect2 oncogene
• ID: MGI:95281

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:164563
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:126925
Molecular Function	GO:0005515	protein binding	IPI	J:4309
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	IPI	J:4309
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:164563
Cellular Component	GO:0005938	cell cortex	IBA	J:265628
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0097149	centralspindlin complex	ISO	J:164563
Cellular Component	GO:0032154	cleavage furrow	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:126925
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0072686	mitotic spindle	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:126925
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0090630	activation of GTPase activity	ISO	J:164563
Biological Process	GO:0090630	activation of GTPase activity	IBA	J:265628
Biological Process	GO:0032147	activation of protein kinase activity	ISO	J:164563
Biological Process	GO:0070830	bicellular tight junction assembly	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0000902	cell morphogenesis	IDA	J:4309
Biological Process	GO:0071277	cellular response to calcium ion	ISO	J:164563
Biological Process	GO:0070301	cellular response to hydrogen peroxide	ISO	J:164563
Biological Process	GO:0071479	cellular response to ionizing radiation	ISO	J:164563
Biological Process	GO:0035556	intracellular signal transduction	IEA	J:72247
Biological Process	GO:0000281	mitotic cytokinesis	ISO	J:164563
Biological Process	GO:0000281	mitotic cytokinesis	IBA	J:265628
Biological Process	GO:0007399	nervous system development	IBA	J:265628
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0032467	positive regulation of cytokinesis	ISO	J:164563
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0045666	positive regulation of neuron differentiation	IMP	J:177235
Biological Process	GO:0042307	positive regulation of protein import into nucleus	IDA	J:126925
Biological Process	GO:0051260	protein homooligomerization	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0051988	regulation of attachment of spindle microtubules to kinetochore	ISO	J:164563
Biological Process	GO:2000431	regulation of cytokinesis, actomyosin contractile ring assembly	IEA	J:72247
Biological Process	GO:0045859	regulation of protein kinase activity	ISO	J:164563