GO Annotations Graph

• Symbol: Eef2
• Name: eukaryotic translation elongation factor 2
• ID: MGI:95288

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008097	5S rRNA binding	ISO	J:155856
Molecular Function	GO:0051015	actin filament binding	ISO	J:155856
Molecular Function	GO:0005525	GTP binding	IEA	J:72247
Molecular Function	GO:0005525	GTP binding	IEA	J:60000
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0003924	GTPase activity	IDA	J:181762
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0002039	p53 binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:181762
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0043022	ribosome binding	ISO	J:155856
Molecular Function	GO:0043022	ribosome binding	ISO	J:164563
Molecular Function	GO:0043022	ribosome binding	IBA	J:265628
Molecular Function	GO:0003723	RNA binding	ISO	J:155856
Molecular Function	GO:0003746	translation elongation factor activity	IBA	J:265628
Cellular Component	GO:0016235	aggresome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:89251
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0042788	polysomal ribosome	ISO	J:155856
Cellular Component	GO:0005844	polysome	IDA	J:181762
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:155856
Cellular Component	GO:1990904	ribonucleoprotein complex	IBA	J:265628
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:142821
Cellular Component	GO:0045202	synapse	IDA	J:263376
Cellular Component	GO:0045202	synapse	EXP	J:263376
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	IMP	J:202604
Biological Process	GO:2000767	positive regulation of cytoplasmic translation	ISO	J:155856
Biological Process	GO:0045727	positive regulation of translation	ISO	J:164563
Biological Process	GO:0045727	positive regulation of translation	ISO	J:155856
Biological Process	GO:0006412	translation	IEA	J:60000
Biological Process	GO:0140242	translation at postsynapse	ISO	J:155856
Biological Process	GO:0006414	translational elongation	IBA	J:265628
Biological Process	GO:0006414	translational elongation	IDA	J:181762