Symbol Name ID |
Erbb2
erb-b2 receptor tyrosine kinase 2 MGI:95410 |
Category | GO ID | Classification Term | Evidence | Reference | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Molecular Function | GO:0005524 | ATP binding | IEA | J:72247 | |||||||||
Molecular Function | GO:0005524 | ATP binding | IEA | J:60000 | |||||||||
Molecular Function | GO:0043125 | ErbB-3 class receptor binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0019838 | growth factor binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0051879 | Hsp90 protein binding | ISO | J:155856 | |||||||||
Molecular Function | GO:0042802 | identical protein binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0016301 | kinase activity | IEA | J:60000 | |||||||||
Molecular Function | GO:0000166 | nucleotide binding | IEA | J:60000 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:168371 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:114070 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:116074 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:187564 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:203534 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:63225 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:198542 | |||||||||
Molecular Function | GO:0046982 | protein heterodimerization activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0004672 | protein kinase activity | IEA | J:72247 | |||||||||
Molecular Function | GO:0004713 | protein tyrosine kinase activity | ISO | J:155856 | |||||||||
Molecular Function | GO:0004713 | protein tyrosine kinase activity | IGI | J:127663 | |||||||||
Molecular Function | GO:0004713 | protein tyrosine kinase activity | IGI | J:82728 | |||||||||
Molecular Function | GO:0004713 | protein tyrosine kinase activity | IDA | J:47407 | |||||||||
Molecular Function | GO:0004713 | protein tyrosine kinase activity | IDA | J:47407 | |||||||||
Molecular Function | GO:0004713 | protein tyrosine kinase activity | IDA | J:34905 | |||||||||
Molecular Function | GO:0004713 | protein tyrosine kinase activity | IDA | J:34905 | |||||||||
Molecular Function | GO:0004713 | protein tyrosine kinase activity | IDA | J:34905 | |||||||||
Molecular Function | GO:0004713 | protein tyrosine kinase activity | IDA | J:317053 | |||||||||
Molecular Function | GO:0004713 | protein tyrosine kinase activity | IDA | J:34905 | |||||||||
Molecular Function | GO:0004713 | protein tyrosine kinase activity | IDA | J:138989 | |||||||||
Molecular Function | GO:0004713 | protein tyrosine kinase activity | IDA | J:319897 | |||||||||
Molecular Function | GO:0004713 | protein tyrosine kinase activity | ISO | J:73065 | |||||||||
Molecular Function | GO:0044877 | protein-containing complex binding | ISO | J:155856 | |||||||||
Molecular Function | GO:0001042 | RNA polymerase I core binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0016740 | transferase activity | IEA | J:60000 | |||||||||
Molecular Function | GO:0004714 | transmembrane receptor protein tyrosine kinase activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0004714 | transmembrane receptor protein tyrosine kinase activity | IBA | J:265628 | |||||||||
Molecular Function | GO:0004888 | transmembrane signaling receptor activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0031625 | ubiquitin protein ligase binding | ISO | J:155856 | |||||||||
Cellular Component | GO:0016324 | apical plasma membrane | ISO | J:155856 | |||||||||
Cellular Component | GO:0016324 | apical plasma membrane | IDA | J:94401 | |||||||||
Cellular Component | GO:0009925 | basal plasma membrane | ISO | J:155856 | |||||||||
Cellular Component | GO:0009925 | basal plasma membrane | IBA | J:265628 | |||||||||
Cellular Component | GO:0016323 | basolateral plasma membrane | ISO | J:164563 | |||||||||
Cellular Component | GO:0016323 | basolateral plasma membrane | ISO | J:155856 | |||||||||
Cellular Component | GO:0042995 | cell projection | IEA | J:60000 | |||||||||
Cellular Component | GO:0005737 | cytoplasm | IDA | J:94401 | |||||||||
Cellular Component | GO:0031410 | cytoplasmic vesicle | IDA | J:198542 | |||||||||
Cellular Component | GO:0005829 | cytosol | ISO | J:164563 | |||||||||
Cellular Component | GO:0005768 | endosome | IEA | J:60000 | |||||||||
Cellular Component | GO:0010008 | endosome membrane | ISO | J:164563 | |||||||||
Cellular Component | GO:0038143 | ERBB3:ERBB2 complex | ISO | J:164563 | |||||||||
Cellular Component | GO:0043219 | lateral loop | ISO | J:155856 | |||||||||
Cellular Component | GO:0016020 | membrane | NAS | J:114116 | |||||||||
Cellular Component | GO:0045121 | membrane raft | ISO | J:155856 | |||||||||
Cellular Component | GO:0005902 | microvillus | ISO | J:155856 | |||||||||
Cellular Component | GO:0043209 | myelin sheath | IDA | J:90038 | |||||||||
Cellular Component | GO:0031594 | neuromuscular junction | IMP | J:180660 | |||||||||
Cellular Component | GO:0031594 | neuromuscular junction | IDA | J:180660 | |||||||||
Cellular Component | GO:0005654 | nucleoplasm | ISO | J:164563 | |||||||||
Cellular Component | GO:0005634 | nucleus | ISO | J:155856 | |||||||||
Cellular Component | GO:0005634 | nucleus | ISO | J:164563 | |||||||||
Cellular Component | GO:0048471 | perinuclear region of cytoplasm | ISO | J:155856 | |||||||||
Cellular Component | GO:0005886 | plasma membrane | ISO | J:164563 | |||||||||
Cellular Component | GO:0005886 | plasma membrane | IDA | J:316874 | |||||||||
Cellular Component | GO:0005886 | plasma membrane | IDA | J:82728 | |||||||||
Cellular Component | GO:0005886 | plasma membrane | IDA | J:47407 | |||||||||
Cellular Component | GO:0005886 | plasma membrane | IDA | J:47407 | |||||||||
Cellular Component | GO:0005886 | plasma membrane | IDA | J:34905 | |||||||||
Cellular Component | GO:0005886 | plasma membrane | IDA | J:34905 | |||||||||
Cellular Component | GO:0005886 | plasma membrane | IDA | J:34905 | |||||||||
Cellular Component | GO:0005886 | plasma membrane | IDA | J:317053 | |||||||||
Cellular Component | GO:0005886 | plasma membrane | IDA | J:34905 | |||||||||
Cellular Component | GO:0005886 | plasma membrane | IDA | J:319897 | |||||||||
Cellular Component | GO:0005886 | plasma membrane | IDA | J:198542 | |||||||||
Cellular Component | GO:0045211 | postsynaptic membrane | ISO | J:155856 | |||||||||
Cellular Component | GO:0042734 | presynaptic membrane | IDA | J:217137 | |||||||||
Cellular Component | GO:0042734 | presynaptic membrane | IDA | J:217137 | |||||||||
Cellular Component | GO:0043235 | receptor complex | ISO | J:164563 | |||||||||
Cellular Component | GO:0043235 | receptor complex | IBA | J:265628 | |||||||||
Cellular Component | GO:0043235 | receptor complex | ISO | J:194542 | |||||||||
Biological Process | GO:0007166 | cell surface receptor signaling pathway | ISO | J:73065 | |||||||||
Biological Process | GO:0071364 | cellular response to epidermal growth factor stimulus | ISO | J:164563 | |||||||||
Biological Process | GO:0071363 | cellular response to growth factor stimulus | ISO | J:164563 | |||||||||
Biological Process | GO:0038134 | ERBB2-EGFR signaling pathway | IGI | J:127663 | |||||||||
Biological Process | GO:0038134 | ERBB2-EGFR signaling pathway | IDA | J:47407 | |||||||||
Biological Process | GO:0038134 | ERBB2-EGFR signaling pathway | IDA | J:34905 | |||||||||
Biological Process | GO:0038134 | ERBB2-EGFR signaling pathway | ISO | J:34905 | |||||||||
Biological Process | GO:0038134 | ERBB2-EGFR signaling pathway | IDA | J:138989 | |||||||||
Biological Process | GO:0038134 | ERBB2-EGFR signaling pathway | IDA | J:319897 | |||||||||
Biological Process | GO:0038133 | ERBB2-ERBB3 signaling pathway | IDA | J:34905 | |||||||||
Biological Process | GO:0038133 | ERBB2-ERBB3 signaling pathway | IDA | J:317053 | |||||||||
Biological Process | GO:0038135 | ERBB2-ERBB4 signaling pathway | IGI | J:82728 | |||||||||
Biological Process | GO:0038135 | ERBB2-ERBB4 signaling pathway | IDA | J:47407 | |||||||||
Biological Process | GO:0038135 | ERBB2-ERBB4 signaling pathway | ISO | J:157327 | |||||||||
Biological Process | GO:0044849 | estrous cycle | ISO | J:155856 | |||||||||
Biological Process | GO:0010001 | glial cell differentiation | ISO | J:155856 | |||||||||
Biological Process | GO:0007507 | heart development | IMP | J:77347 | |||||||||
Biological Process | GO:0007507 | heart development | IMP | J:45302 | |||||||||
Biological Process | GO:0033080 | immature T cell proliferation in thymus | IMP | J:116829 | |||||||||
Biological Process | GO:0035556 | intracellular signal transduction | ISO | J:164563 | |||||||||
Biological Process | GO:0008045 | motor neuron axon guidance | IMP | J:60191 | |||||||||
Biological Process | GO:0008045 | motor neuron axon guidance | IMP | J:60191 | |||||||||
Biological Process | GO:0007275 | multicellular organism development | IBA | J:265628 | |||||||||
Biological Process | GO:0042552 | myelination | IMP | J:75421 | |||||||||
Biological Process | GO:0043066 | negative regulation of apoptotic process | ISO | J:155856 | |||||||||
Biological Process | GO:0043066 | negative regulation of apoptotic process | IBA | J:265628 | |||||||||
Biological Process | GO:0033088 | negative regulation of immature T cell proliferation in thymus | IMP | J:116829 | |||||||||
Biological Process | GO:0007399 | nervous system development | IMP | J:94397 | |||||||||
Biological Process | GO:0007399 | nervous system development | IMP | J:94397 | |||||||||
Biological Process | GO:0007399 | nervous system development | IMP | J:94397 | |||||||||
Biological Process | GO:0007399 | nervous system development | IMP | J:94397 | |||||||||
Biological Process | GO:0007399 | nervous system development | IMP | J:94397 | |||||||||
Biological Process | GO:0007399 | nervous system development | IMP | J:94397 | |||||||||
Biological Process | GO:0022008 | neurogenesis | IBA | J:265628 | |||||||||
Biological Process | GO:0007528 | neuromuscular junction development | IMP | J:60191 | |||||||||
Biological Process | GO:0030182 | neuron differentiation | IBA | J:265628 | |||||||||
Biological Process | GO:0099645 | neurotransmitter receptor localization to postsynaptic specialization membrane | IDA | J:180660 | |||||||||
Biological Process | GO:0099645 | neurotransmitter receptor localization to postsynaptic specialization membrane | IMP | J:180660 | |||||||||
Biological Process | GO:0048709 | oligodendrocyte differentiation | IMP | J:145866 | |||||||||
Biological Process | GO:0018108 | peptidyl-tyrosine phosphorylation | ISO | J:164563 | |||||||||
Biological Process | GO:0007422 | peripheral nervous system development | ISO | J:155856 | |||||||||
Biological Process | GO:0007422 | peripheral nervous system development | IMP | J:45302 | |||||||||
Biological Process | GO:0014065 | phosphatidylinositol 3-kinase signaling | ISO | J:164563 | |||||||||
Biological Process | GO:0016310 | phosphorylation | IEA | J:60000 | |||||||||
Biological Process | GO:0045785 | positive regulation of cell adhesion | ISO | J:164563 | |||||||||
Biological Process | GO:0030307 | positive regulation of cell growth | ISO | J:164563 | |||||||||
Biological Process | GO:0008284 | positive regulation of cell population proliferation | ISO | J:155856 | |||||||||
Biological Process | GO:0008284 | positive regulation of cell population proliferation | IBA | J:265628 | |||||||||
Biological Process | GO:0050679 | positive regulation of epithelial cell proliferation | ISO | J:164563 | |||||||||
Biological Process | GO:0010628 | positive regulation of gene expression | IMP | J:210551 | |||||||||
Biological Process | GO:0043547 | positive regulation of GTPase activity | IMP | J:178104 | |||||||||
Biological Process | GO:0033674 | positive regulation of kinase activity | IBA | J:265628 | |||||||||
Biological Process | GO:0043406 | positive regulation of MAP kinase activity | ISO | J:164563 | |||||||||
Biological Process | GO:0043410 | positive regulation of MAPK cascade | ISO | J:155856 | |||||||||
Biological Process | GO:0043410 | positive regulation of MAPK cascade | IBA | J:265628 | |||||||||
Biological Process | GO:0014068 | positive regulation of phosphatidylinositol 3-kinase signaling | ISO | J:155856 | |||||||||
Biological Process | GO:0001934 | positive regulation of protein phosphorylation | IMP | J:178104 | |||||||||
Biological Process | GO:0090314 | positive regulation of protein targeting to membrane | ISO | J:164563 | |||||||||
Biological Process | GO:0046579 | positive regulation of Ras protein signal transduction | ISO | J:155856 | |||||||||
Biological Process | GO:0045943 | positive regulation of transcription by RNA polymerase I | ISO | J:164563 | |||||||||
Biological Process | GO:0045727 | positive regulation of translation | ISO | J:164563 | |||||||||
Biological Process | GO:0046777 | protein autophosphorylation | ISO | J:155856 | |||||||||
Biological Process | GO:0046777 | protein autophosphorylation | ISO | J:164563 | |||||||||
Biological Process | GO:0006468 | protein phosphorylation | IEA | J:72247 | |||||||||
Biological Process | GO:0070372 | regulation of ERK1 and ERK2 cascade | ISO | J:164563 | |||||||||
Biological Process | GO:0032886 | regulation of microtubule-based process | ISO | J:164563 | |||||||||
Biological Process | GO:0048678 | response to axon injury | ISO | J:155856 | |||||||||
Biological Process | GO:0007165 | signal transduction | ISO | J:164563 | |||||||||
Biological Process | GO:0048485 | sympathetic nervous system development | ISO | J:155856 | |||||||||
Biological Process | GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | ISO | J:164563 | |||||||||
Biological Process | GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | IBA | J:265628 | |||||||||
Biological Process | GO:0042060 | wound healing | ISO | J:164563 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 12/10/2024 MGI 6.24 |
![]() |
|