GO Annotations Graph

• Symbol: Ercc3
• Name: excision repair cross-complementing rodent repair deficiency, complementation group 3
• ID: MGI:95414

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043138	3'-5' DNA helicase activity	ISO	J:164563
Molecular Function	GO:0043138	3'-5' DNA helicase activity	IBA	J:265628
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	IMP	J:198536
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003678	DNA helicase activity	IEA	J:72247
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:181994
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0000112	nucleotide-excision repair factor 3 complex	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005669	transcription factor TFIID complex	ISO	J:164563
Cellular Component	GO:0000439	transcription factor TFIIH core complex	ISO	J:155856
Cellular Component	GO:0000439	transcription factor TFIIH core complex	ISO	J:164563
Cellular Component	GO:0005675	transcription factor TFIIH holo complex	ISO	J:164563
Cellular Component	GO:0005675	transcription factor TFIIH holo complex	IBA	J:265628
Cellular Component	GO:0097550	transcription preinitiation complex	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0006265	DNA topological change	ISO	J:164563
Biological Process	GO:0048568	embryonic organ development	IBA	J:265628
Biological Process	GO:0035315	hair cell differentiation	ISO	J:164563
Biological Process	GO:0035315	hair cell differentiation	IBA	J:265628
Biological Process	GO:0006289	nucleotide-excision repair	ISO	J:164563
Biological Process	GO:0000717	nucleotide-excision repair, DNA duplex unwinding	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0008104	protein localization	ISO	J:164563
Biological Process	GO:1901990	regulation of mitotic cell cycle phase transition	ISO	J:164563
Biological Process	GO:0006979	response to oxidative stress	ISO	J:164563
Biological Process	GO:0009411	response to UV	ISO	J:164563
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006362	transcription elongation by RNA polymerase I	EXP	J:198536
Biological Process	GO:0006367	transcription initiation at RNA polymerase II promoter	IBA	J:265628
Biological Process	GO:0006283	transcription-coupled nucleotide-excision repair	ISO	J:164563
Biological Process	GO:0009650	UV protection	IGI	J:1626