GO Annotations Graph

• Symbol: Fasn
• Name: fatty acid synthase
• ID: MGI:95485

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008693	(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity	IEA	J:72245
Molecular Function	GO:0047451	(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	IEA	J:72245
Molecular Function	GO:0019171	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	IEA	J:72245
Molecular Function	GO:0008659	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity	IEA	J:72245
Molecular Function	GO:0004317	(3R)-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity	IEA	J:72245
Molecular Function	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	IEA	J:72245
Molecular Function	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	IEA	J:72247
Molecular Function	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	IEA	J:72245
Molecular Function	GO:0004313	[acyl-carrier-protein] S-acetyltransferase activity	IEA	J:72245
Molecular Function	GO:0004314	[acyl-carrier-protein] S-malonyltransferase activity	ISO	J:155856
Molecular Function	GO:0016297	acyl-[acyl-carrier-protein] hydrolase activity	IEA	J:72245
Molecular Function	GO:0016746	acyltransferase activity	IEA	J:72247
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0047117	enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity	IEA	J:72245
Molecular Function	GO:0004312	fatty acid synthase activity	ISO	J:155856
Molecular Function	GO:0004312	fatty acid synthase activity	IBA	J:265628
Molecular Function	GO:0004312	fatty acid synthase activity	TAS	J:219976
Molecular Function	GO:0004312	fatty acid synthase activity	TAS	J:219976
Molecular Function	GO:0004312	fatty acid synthase activity	TAS	J:219976
Molecular Function	GO:0004312	fatty acid synthase activity	IDA	J:129840
Molecular Function	GO:0004312	fatty acid synthase activity	IMP	J:127793
Molecular Function	GO:0004312	fatty acid synthase activity	IDA	J:184939
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0016295	myristoyl-[acyl-carrier-protein] hydrolase activity	IEA	J:72245
Molecular Function	GO:0004320	oleoyl-[acyl-carrier-protein] hydrolase activity	IEA	J:72245
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016296	palmitoyl-[acyl-carrier-protein] hydrolase activity	IEA	J:72245
Molecular Function	GO:0031177	phosphopantetheine binding	IEA	J:72247
Molecular Function	GO:0016419	S-malonyltransferase activity	IEA	J:72245
Molecular Function	GO:0016740	transferase activity	IEA	J:72247
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:129840
Cellular Component	GO:0042587	glycogen granule	IDA	J:101235
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0006084	acetyl-CoA metabolic process	ISO	J:155856
Biological Process	GO:0009058	biosynthetic process	IEA	J:72247
Biological Process	GO:0071353	cellular response to interleukin-4	IDA	J:62630
Biological Process	GO:0090557	establishment of endothelial intestinal barrier	IMP	J:219976
Biological Process	GO:0008611	ether lipid biosynthetic process	IMP	J:219976
Biological Process	GO:0008611	ether lipid biosynthetic process	IMP	J:219976
Biological Process	GO:0006633	fatty acid biosynthetic process	ISO	J:155856
Biological Process	GO:0006633	fatty acid biosynthetic process	IBA	J:265628
Biological Process	GO:0006633	fatty acid biosynthetic process	IDA	J:184939
Biological Process	GO:0006631	fatty acid metabolic process	IEA	J:60000
Biological Process	GO:0002068	glandular epithelial cell development	IMP	J:219976
Biological Process	GO:0006954	inflammatory response	IMP	J:219976
Biological Process	GO:0008610	lipid biosynthetic process	IDA	J:129840
Biological Process	GO:0008610	lipid biosynthetic process	IMP	J:127793
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0030879	mammary gland development	IMP	J:213169
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0044788	modulation by host of viral process	ISO	J:164563
Biological Process	GO:0030224	monocyte differentiation	IMP	J:219976
Biological Process	GO:0030223	neutrophil differentiation	IMP	J:219976
Biological Process	GO:0009888	tissue development	IMP	J:219976