GO Annotations Graph

• Symbol: Fbn2
• Name: fibrillin 2
• ID: MGI:95490

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	TAS	J:68881
Molecular Function	GO:0005509	calcium ion binding	TAS	J:69450
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265607
Molecular Function	GO:0005201	extracellular matrix structural constituent	IBA	J:265628
Molecular Function	GO:0005179	hormone activity	ISO	J:164563
Molecular Function	GO:0005179	hormone activity	IDA	J:313847
Molecular Function	GO:0005515	protein binding	IPI	J:221347
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:213088
Cellular Component	GO:0005576	extracellular region	TAS	J:68881
Cellular Component	GO:0005576	extracellular region	IDA	J:203031
Cellular Component	GO:0005576	extracellular region	IDA	J:203031
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0001527	microfibril	ISO	J:164563
Cellular Component	GO:0001527	microfibril	TAS	J:165256
Cellular Component	GO:0001527	microfibril	IDA	J:203031
Cellular Component	GO:0001527	microfibril	IDA	J:226844
Cellular Component	GO:0001527	microfibril	TAS	J:25216
Cellular Component	GO:0001527	microfibril	IDA	J:226844
Biological Process	GO:0060346	bone trabecula formation	IMP	J:165256
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:68881
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:68881
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:69450
Biological Process	GO:0042593	glucose homeostasis	IDA	J:313847
Biological Process	GO:0035108	limb morphogenesis	IMP	J:60747
Biological Process	GO:0001890	placenta development	ISO	J:164563
Biological Process	GO:0030501	positive regulation of bone mineralization	IMP	J:165256
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IMP	J:165256
Biological Process	GO:1901163	regulation of trophoblast cell migration	ISO	J:164563
Biological Process	GO:0035583	sequestering of TGFbeta in extracellular matrix	IMP	J:165256