Fcgr2b GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Fcgr2b
Fc receptor, IgG, low affinity IIb
MGI:95499

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001540	amyloid-beta binding	ISO	J:164563
Molecular Function	GO:0019864	IgG binding	ISO	J:164563
Molecular Function	GO:0019864	IgG binding	ISO	J:155856
Molecular Function	GO:0019864	IgG binding	IDA	J:86280
Molecular Function	GO:0019865	immunoglobulin binding	ISO	J:155856
Molecular Function	GO:0019772	low-affinity IgG receptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:84951
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IBA	J:265628
Cellular Component	GO:0044297	cell body	IDA	J:123637
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0043197	dendritic spine	IDA	J:123637
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:31133
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:35057
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:31133
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:123637
Cellular Component	GO:0005886	plasma membrane	IDA	J:242013
Cellular Component	GO:0005886	plasma membrane	IDA	J:123637
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IC	J:31133
Cellular Component	GO:0005886	plasma membrane	IC	J:31133
Cellular Component	GO:0055037	recycling endosome	ISO	J:155856
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	IMP	J:87421
Biological Process	GO:0042100	B cell proliferation	IMP	J:102982
Biological Process	GO:0007166	cell surface receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007166	cell surface receptor signaling pathway	IMP	J:31133
Biological Process	GO:1904646	cellular response to amyloid-beta	IMP	J:201623
Biological Process	GO:1904646	cellular response to amyloid-beta	ISO	J:155856
Biological Process	GO:0071219	cellular response to molecule of bacterial origin	IMP	J:102982
Biological Process	GO:0021549	cerebellum development	IMP	J:123637
Biological Process	GO:0006952	defense response	IMP	J:76486
Biological Process	GO:0016358	dendrite development	IMP	J:123637
Biological Process	GO:0032456	endocytic recycling	ISO	J:155856
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:102982
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:102982
Biological Process	GO:0160006	Fc receptor-mediated immune complex endocytosis	IDA	J:242013
Biological Process	GO:0002434	immune complex clearance	ISO	J:155856
Biological Process	GO:0016064	immunoglobulin mediated immune response	IMP	J:56162
Biological Process	GO:0016064	immunoglobulin mediated immune response	IMP	J:87421
Biological Process	GO:0002377	immunoglobulin production	IMP	J:102982
Biological Process	GO:0032613	interleukin-10 production	IMP	J:102982
Biological Process	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	IMP	J:102982
Biological Process	GO:0030889	negative regulation of B cell proliferation	IMP	J:102982
Biological Process	GO:0030889	negative regulation of B cell proliferation	IMP	J:31133
Biological Process	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	IMP	J:102982
Biological Process	GO:0050777	negative regulation of immune response	IMP	J:56162
Biological Process	GO:0050777	negative regulation of immune response	IMP	J:31133
Biological Process	GO:0050777	negative regulation of immune response	IMP	J:76486
Biological Process	GO:0002638	negative regulation of immunoglobulin production	IMP	J:102982
Biological Process	GO:0002862	negative regulation of inflammatory response to antigenic stimulus	IMP	J:107174
Biological Process	GO:0032693	negative regulation of interleukin-10 production	IMP	J:102982
Biological Process	GO:0033030	negative regulation of neutrophil apoptotic process	ISO	J:155856
Biological Process	GO:0050765	negative regulation of phagocytosis	IMP	J:102982
Biological Process	GO:0001811	negative regulation of type I hypersensitivity	IMP	J:31133
Biological Process	GO:0006909	phagocytosis	IMP	J:102982
Biological Process	GO:0006909	phagocytosis	IMP	J:102982
Biological Process	GO:0006911	phagocytosis, engulfment	IDA	J:35057
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IMP	J:201623
Biological Process	GO:0046330	positive regulation of JNK cascade	IMP	J:201623
Biological Process	GO:1901216	positive regulation of neuron death	ISO	J:155856
Biological Process	GO:1901216	positive regulation of neuron death	IMP	J:201623
Biological Process	GO:0050766	positive regulation of phagocytosis	IDA	J:35057
Biological Process	GO:1905898	positive regulation of response to endoplasmic reticulum stress	ISO	J:155856
Biological Process	GO:1905898	positive regulation of response to endoplasmic reticulum stress	IMP	J:201623
Biological Process	GO:0006898	receptor-mediated endocytosis	ISO	J:155856
Biological Process	GO:1902950	regulation of dendritic spine maintenance	IMP	J:201623
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	IMP	J:201623
Biological Process	GO:0009617	response to bacterium	IMP	J:102982

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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