Fgf2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Fgf2
fibroblast growth factor 2
MGI:95516

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042056	chemoattractant activity	ISO	J:164563
Molecular Function	GO:0019956	chemokine binding	ISO	J:164563
Molecular Function	GO:0005125	cytokine activity	ISO	J:164563
Molecular Function	GO:0005104	fibroblast growth factor receptor binding	IBA	J:265628
Molecular Function	GO:0005104	fibroblast growth factor receptor binding	ISO	J:73065
Molecular Function	GO:0005104	fibroblast growth factor receptor binding	ISO	J:73065
Molecular Function	GO:0005104	fibroblast growth factor receptor binding	ISO	J:73065
Molecular Function	GO:0008083	growth factor activity	ISO	J:164563
Molecular Function	GO:0008083	growth factor activity	IBA	J:265628
Molecular Function	GO:0008083	growth factor activity	IDA	J:96008
Molecular Function	GO:0008201	heparin binding	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005178	integrin binding	ISO	J:164563
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:171305
Molecular Function	GO:0005515	protein binding	IPI	J:250431
Molecular Function	GO:0005515	protein binding	IPI	J:85277
Molecular Function	GO:0005515	protein binding	IPI	J:13170
Molecular Function	GO:0090722	receptor-receptor interaction	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	ISO	J:73065
Cellular Component	GO:0005615	extracellular space	IDA	J:94299
Cellular Component	GO:0005615	extracellular space	IDA	J:79996
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Biological Process	GO:0001525	angiogenesis	IGI	J:109532
Biological Process	GO:0060978	angiogenesis involved in coronary vascular morphogenesis	ISO	J:155856
Biological Process	GO:0009887	animal organ morphogenesis	IBA	J:265628
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	ISO	J:164563
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:119299
Biological Process	GO:0060038	cardiac muscle cell proliferation	TAS	J:169941
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0008283	cell population proliferation	IGI	J:94813
Biological Process	GO:0008283	cell population proliferation	IGI	J:94813
Biological Process	GO:0008283	cell population proliferation	IDA	J:101732
Biological Process	GO:0008283	cell population proliferation	IGI	J:52548
Biological Process	GO:0008283	cell population proliferation	IGI	J:52548
Biological Process	GO:0008283	cell population proliferation	IGI	J:163175
Biological Process	GO:0008283	cell population proliferation	IGI	J:89246
Biological Process	GO:0021930	cerebellar granule cell precursor proliferation	IDA	J:52548
Biological Process	GO:0021930	cerebellar granule cell precursor proliferation	IDA	J:52548
Biological Process	GO:0060591	chondroblast differentiation	ISO	J:164563
Biological Process	GO:0060128	corticotropin hormone secreting cell differentiation	IDA	J:46975
Biological Process	GO:0009792	embryo development ending in birth or egg hatching	ISO	J:155856
Biological Process	GO:0043542	endothelial cell migration	IDA	J:111764
Biological Process	GO:0001935	endothelial cell proliferation	IDA	J:111764
Biological Process	GO:0001935	endothelial cell proliferation	IDA	J:111764
Biological Process	GO:0050673	epithelial cell proliferation	IGI	J:94813
Biological Process	GO:0050673	epithelial cell proliferation	IGI	J:94813
Biological Process	GO:0050673	epithelial cell proliferation	IDA	J:119174
Biological Process	GO:0070371	ERK1 and ERK2 cascade	IDA	J:119299
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IBA	J:265628
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	ISO	J:73065
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	ISO	J:73065
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	ISO	J:73065
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	ISO	J:73065
Biological Process	GO:0010001	glial cell differentiation	IMP	J:84705
Biological Process	GO:0014843	growth factor dependent regulation of skeletal muscle satellite cell proliferation	ISO	J:164563
Biological Process	GO:0030214	hyaluronan catabolic process	ISO	J:164563
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IDA	J:79996
Biological Process	GO:0032958	inositol phosphate biosynthetic process	ISO	J:164563
Biological Process	GO:0030324	lung development	IGI	J:119174
Biological Process	GO:0030324	lung development	IDA	J:94299
Biological Process	GO:1904977	lymphatic endothelial cell migration	IDA	J:111764
Biological Process	GO:0060644	mammary gland epithelial cell differentiation	IDA	J:652
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043537	negative regulation of blood vessel endothelial cell migration	ISO	J:164563
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:52548
Biological Process	GO:0010764	negative regulation of fibroblast migration	ISO	J:164563
Biological Process	GO:2000647	negative regulation of stem cell proliferation	IGI	J:163175
Biological Process	GO:0061045	negative regulation of wound healing	ISO	J:164563
Biological Process	GO:0007405	neuroblast proliferation	IGI	J:89246
Biological Process	GO:0060563	neuroepithelial cell differentiation	IDA	J:79996
Biological Process	GO:0001759	organ induction	IDA	J:94299
Biological Process	GO:0001649	osteoblast differentiation	IGI	J:163175
Biological Process	GO:0001649	osteoblast differentiation	IGI	J:163175
Biological Process	GO:0038001	paracrine signaling	ISO	J:155856
Biological Process	GO:0006661	phosphatidylinositol biosynthetic process	ISO	J:164563
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0045766	positive regulation of angiogenesis	IGI	J:109532
Biological Process	GO:0045766	positive regulation of angiogenesis	IDA	J:88338
Biological Process	GO:0045766	positive regulation of angiogenesis	IGI	J:109484
Biological Process	GO:0045766	positive regulation of angiogenesis	IDA	J:87621
Biological Process	GO:0045766	positive regulation of angiogenesis	IGI	J:119174
Biological Process	GO:0045766	positive regulation of angiogenesis	IDA	J:109532
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	ISO	J:164563
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IDA	J:119299
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	ISO	J:164563
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	ISO	J:155856
Biological Process	GO:0051781	positive regulation of cell division	IEA	J:60000
Biological Process	GO:0042660	positive regulation of cell fate specification	ISO	J:139252
Biological Process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:73065
Biological Process	GO:0008284	positive regulation of cell population proliferation	IDA	J:46975
Biological Process	GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	IDA	J:52548
Biological Process	GO:2000573	positive regulation of DNA biosynthetic process	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TAS	J:169941
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:2001028	positive regulation of endothelial cell chemotaxis	ISO	J:164563
Biological Process	GO:2000546	positive regulation of endothelial cell chemotaxis to fibroblast growth factor	ISO	J:164563
Biological Process	GO:0010595	positive regulation of endothelial cell migration	ISO	J:164563
Biological Process	GO:0010595	positive regulation of endothelial cell migration	IDA	J:111764
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:164563
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	IDA	J:111764
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IDA	J:119174
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IGI	J:94813
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IGI	J:94813
Biological Process	GO:1905278	positive regulation of epithelial tube formation	ISO	J:164563
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IDA	J:287039
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IDA	J:119299
Biological Process	GO:0010628	positive regulation of gene expression	IBA	J:265628
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:41974
Biological Process	GO:0045609	positive regulation of inner ear auditory receptor cell differentiation	IDA	J:79996
Biological Process	GO:1902748	positive regulation of lens fiber cell differentiation	ISO	J:164563
Biological Process	GO:0043406	positive regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	IDA	J:105250
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	IGI	J:89246
Biological Process	GO:1902913	positive regulation of neuroepithelial cell differentiation	IDA	J:79996
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IGI	J:163175
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	ISO	J:164563
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	ISO	J:164563
Biological Process	GO:0010863	positive regulation of phospholipase C activity	ISO	J:164563
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	IDA	J:119299
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IDA	J:287039
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IBA	J:265628
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IDA	J:96008
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:1903672	positive regulation of sprouting angiogenesis	ISO	J:164563
Biological Process	GO:2000738	positive regulation of stem cell differentiation	IDA	J:99916
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IDA	J:101732
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:36231
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:39349
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:56303
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:1905564	positive regulation of vascular endothelial cell proliferation	ISO	J:164563
Biological Process	GO:0043491	protein kinase B signaling	IDA	J:119299
Biological Process	GO:0051726	regulation of cell cycle	IDA	J:46975
Biological Process	GO:0030334	regulation of cell migration	IBA	J:265628
Biological Process	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor	ISO	J:164563
Biological Process	GO:0046668	regulation of retinal cell programmed cell death	IDA	J:73377
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	ISO	J:164563
Biological Process	GO:0048678	response to axon injury	IMP	J:104421
Biological Process	GO:0048864	stem cell development	IMP	J:84335
Biological Process	GO:0048863	stem cell differentiation	IDA	J:99916
Biological Process	GO:0072089	stem cell proliferation	IDA	J:101732
Biological Process	GO:0072089	stem cell proliferation	IGI	J:163175
Biological Process	GO:0021762	substantia nigra development	IMP	J:117417
Biological Process	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation	IDA	J:46975
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:56303
Biological Process	GO:0042060	wound healing	ISO	J:164563

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