Fgfr1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Fgfr1
fibroblast growth factor receptor 1
MGI:95522

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0050839	cell adhesion molecule binding	ISO	J:155856
Molecular Function	GO:0017134	fibroblast growth factor binding	IPI	J:117479
Molecular Function	GO:0017134	fibroblast growth factor binding	ISO	J:164563
Molecular Function	GO:0017134	fibroblast growth factor binding	IBA	J:265628
Molecular Function	GO:0017134	fibroblast growth factor binding	IDA	J:31506
Molecular Function	GO:0005007	fibroblast growth factor receptor activity	ISO	J:164563
Molecular Function	GO:0005007	fibroblast growth factor receptor activity	IBA	J:265628
Molecular Function	GO:0005007	fibroblast growth factor receptor activity	ISO	J:73065
Molecular Function	GO:0005007	fibroblast growth factor receptor activity	IDA	J:31506
Molecular Function	GO:0008201	heparin binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:156501
Molecular Function	GO:0005515	protein binding	IPI	J:117479
Molecular Function	GO:0005515	protein binding	IPI	J:112631
Molecular Function	GO:0005515	protein binding	IPI	J:200439
Molecular Function	GO:0005515	protein binding	IPI	J:121336
Molecular Function	GO:0005515	protein binding	IPI	J:105263
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0090722	receptor-receptor interaction	ISO	J:164563
Molecular Function	GO:0042169	SH2 domain binding	IPI	J:149152
Molecular Function	GO:0042169	SH2 domain binding	IPI	J:149152
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:155856
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IEA	J:72245
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-420393
Cellular Component	GO:0005886	plasma membrane	IPI	J:31506
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Biological Process	GO:0001525	angiogenesis	IGI	J:109722
Biological Process	GO:0060117	auditory receptor cell development	IMP	J:95895
Biological Process	GO:0048514	blood vessel morphogenesis	IMP	J:103237
Biological Process	GO:0007420	brain development	IMP	J:83004
Biological Process	GO:0060445	branching involved in salivary gland morphogenesis	IMP	J:140258
Biological Process	GO:0060445	branching involved in salivary gland morphogenesis	IMP	J:79832
Biological Process	GO:0055074	calcium ion homeostasis	IGI	J:201223
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:95803
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:95803
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:109722
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:95803
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:95803
Biological Process	GO:0048469	cell maturation	IMP	J:103237
Biological Process	GO:0008283	cell population proliferation	IGI	J:109722
Biological Process	GO:0071529	cementum mineralization	IMP	J:279653
Biological Process	GO:0071529	cementum mineralization	IDA	J:279653
Biological Process	GO:0071529	cementum mineralization	IMP	J:279653
Biological Process	GO:0071529	cementum mineralization	IMP	J:279653
Biological Process	GO:0021954	central nervous system neuron development	ISO	J:155856
Biological Process	GO:0002062	chondrocyte differentiation	IGI	J:122952
Biological Process	GO:0071344	diphosphate metabolic process	IMP	J:279653
Biological Process	GO:0071344	diphosphate metabolic process	IDA	J:279653
Biological Process	GO:0043583	ear development	IMP	J:223062
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:102949
Biological Process	GO:0001837	epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	ISO	J:73065
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:31506
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:95803
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	ISO	J:73065
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	ISO	J:73065
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:109722
Biological Process	GO:0035607	fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	IMP	J:159839
Biological Process	GO:0010467	gene expression	IDA	J:279653
Biological Process	GO:0010467	gene expression	IMP	J:279653
Biological Process	GO:0048699	generation of neurons	IMP	J:105216
Biological Process	GO:0001701	in utero embryonic development	IGI	J:123685
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:78879
Biological Process	GO:0030324	lung development	IGI	J:107406
Biological Process	GO:0030324	lung development	IMP	J:94299
Biological Process	GO:0030324	lung development	IGI	J:107406
Biological Process	GO:0060484	lung-associated mesenchyme development	IGI	J:137691
Biological Process	GO:0048762	mesenchymal cell differentiation	IGI	J:107078
Biological Process	GO:0010463	mesenchymal cell proliferation	IGI	J:107406
Biological Process	GO:0010463	mesenchymal cell proliferation	IMP	J:132412
Biological Process	GO:0030901	midbrain development	IMP	J:123685
Biological Process	GO:0030901	midbrain development	IGI	J:123685
Biological Process	GO:0030901	midbrain development	IMP	J:123685
Biological Process	GO:0042474	middle ear morphogenesis	IMP	J:95895
Biological Process	GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	ISO	J:155856
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0090272	negative regulation of fibroblast growth factor production	IGI	J:206158
Biological Process	GO:0010629	negative regulation of gene expression	IGI	J:206158
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:132412
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:159839
Biological Process	GO:0031175	neuron projection development	ISO	J:155856
Biological Process	GO:0031175	neuron projection development	IGI	J:170083
Biological Process	GO:0021769	orbitofrontal cortex development	IMP	J:159839
Biological Process	GO:0001759	organ induction	IMP	J:94299
Biological Process	GO:0042473	outer ear morphogenesis	IMP	J:95895
Biological Process	GO:0048339	paraxial mesoderm development	IGI	J:119568
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	ISO	J:164563
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	ISO	J:155856
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IGI	J:95803
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IGI	J:109722
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IGI	J:95803
Biological Process	GO:0045787	positive regulation of cell cycle	IMP	J:159839
Biological Process	GO:0045597	positive regulation of cell differentiation	IBA	J:265628
Biological Process	GO:0008284	positive regulation of cell population proliferation	TAS	J:184501
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:159839
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGI	J:153198
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGI	J:153198
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGI	J:153198
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGI	J:153198
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:73065
Biological Process	GO:0008284	positive regulation of cell population proliferation	IDA	J:31506
Biological Process	GO:2000546	positive regulation of endothelial cell chemotaxis to fibroblast growth factor	ISO	J:164563
Biological Process	GO:0010763	positive regulation of fibroblast migration	ISO	J:155856
Biological Process	GO:2000491	positive regulation of hepatic stellate cell activation	ISO	J:155856
Biological Process	GO:0050729	positive regulation of inflammatory response	ISO	J:155856
Biological Process	GO:0033674	positive regulation of kinase activity	IBA	J:265628
Biological Process	GO:0043406	positive regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	ISO	J:155856
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IGI	J:107406
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IMP	J:132412
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IGI	J:107406
Biological Process	GO:1903465	positive regulation of mitotic cell cycle DNA replication	IDA	J:31506
Biological Process	GO:0045666	positive regulation of neuron differentiation	ISO	J:164563
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	IGI	J:170083
Biological Process	GO:2000830	positive regulation of parathyroid hormone secretion	IGI	J:206158
Biological Process	GO:0010863	positive regulation of phospholipase C activity	ISO	J:164563
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IGI	J:107406
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IGI	J:107406
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IMP	J:132412
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:1905564	positive regulation of vascular endothelial cell proliferation	ISO	J:164563
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	IDA	J:140258
Biological Process	GO:0042127	regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0050678	regulation of epithelial cell proliferation	IMP	J:78879
Biological Process	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	IMP	J:132412
Biological Process	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	IMP	J:102949
Biological Process	GO:0010468	regulation of gene expression	IMP	J:142755
Biological Process	GO:0048378	regulation of lateral mesodermal cell fate specification	IGI	J:119568
Biological Process	GO:0010966	regulation of phosphate transport	IGI	J:206158
Biological Process	GO:0051174	regulation of phosphorus metabolic process	IGI	J:206158
Biological Process	GO:0051930	regulation of sensory perception of pain	ISO	J:155856
Biological Process	GO:0072091	regulation of stem cell proliferation	ISO	J:155856
Biological Process	GO:1904383	response to sodium phosphate	IGI	J:201223
Biological Process	GO:1904383	response to sodium phosphate	IDA	J:201223
Biological Process	GO:1904383	response to sodium phosphate	IGI	J:201223
Biological Process	GO:0007435	salivary gland morphogenesis	IMP	J:79832
Biological Process	GO:0007605	sensory perception of sound	IMP	J:95895
Biological Process	GO:0048863	stem cell differentiation	IGI	J:107078
Biological Process	GO:0019827	stem cell population maintenance	ISO	J:155856
Biological Process	GO:0072089	stem cell proliferation	IMP	J:132412
Biological Process	GO:0072089	stem cell proliferation	IGI	J:107406
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628
Biological Process	GO:0001657	ureteric bud development	IGI	J:107078
Biological Process	GO:0060979	vasculogenesis involved in coronary vascular morphogenesis	TAS	J:169941
Biological Process	GO:0021847	ventricular zone neuroblast division	IMP	J:159839
Biological Process	GO:0070640	vitamin D3 metabolic process	IGI	J:206158

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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