GO Annotations Graph

• Symbol: Fgr
• Name: FGR proto-oncogene, Src family tyrosine kinase
• ID: MGI:95527

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0034988	Fc-gamma receptor I complex binding	ISO	J:164563
Molecular Function	GO:0034987	immunoglobulin receptor binding	IDA	J:177211
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	IDA	J:94595
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0001784	phosphotyrosine residue binding	IDA	J:110529
Molecular Function	GO:0001784	phosphotyrosine residue binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:131738
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0019901	protein kinase binding	IPI	J:110529
Molecular Function	GO:0019901	protein kinase binding	IDA	J:110529
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:155856
Molecular Function	GO:0005102	signaling receptor binding	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0015629	actin cytoskeleton	IDA	J:94595
Cellular Component	GO:0016235	aggresome	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:177211
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:94595
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032587	ruffle membrane	IDA	J:94595
Biological Process	GO:0030282	bone mineralization	IMP	J:112868
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IMP	J:16994
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IGI	J:16994
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IBA	J:265628
Biological Process	GO:0007229	integrin-mediated signaling pathway	IMP	J:110529
Biological Process	GO:0007229	integrin-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0007229	integrin-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0032815	negative regulation of natural killer cell activation	IMP	J:131738
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	IDA	J:94595
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0030335	positive regulation of cell migration	IMP	J:94595
Biological Process	GO:0001819	positive regulation of cytokine production	IDA	J:177211
Biological Process	GO:0043306	positive regulation of mast cell degranulation	IDA	J:177211
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	ISO	J:164563
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	ISO	J:164563
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	TAS	J:94595
Biological Process	GO:0008360	regulation of cell shape	IMP	J:110529
Biological Process	GO:0045088	regulation of innate immune response	IMP	J:177211
Biological Process	GO:0050764	regulation of phagocytosis	IMP	J:110529
Biological Process	GO:0045859	regulation of protein kinase activity	IDA	J:110529
Biological Process	GO:0048705	skeletal system morphogenesis	IMP	J:112868
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628