GO Annotations Graph

• Symbol: Flt3l
• Name: FMS-like tyrosine kinase 3 ligand
• ID: MGI:95560

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	IEA	J:72247
Molecular Function	GO:0005125	cytokine activity	IEA	J:60000
Molecular Function	GO:0030971	receptor tyrosine kinase binding	IBA	J:265628
Molecular Function	GO:0030971	receptor tyrosine kinase binding	IDA	J:23709
Molecular Function	GO:0030971	receptor tyrosine kinase binding	IPI	J:16458
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0009986	cell surface	IDA	J:27743
Cellular Component	GO:0009986	cell surface	IDA	J:27743
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:16458
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9604768
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9604980
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9605258
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9606621
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9606623
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9606789
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9607226
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9609272
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9645128
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9645133
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9645136
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:16458
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0035162	embryonic hemopoiesis	ISO	J:164563
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	IGI	J:166692
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	IDA	J:166692
Biological Process	GO:0030098	lymphocyte differentiation	IMP	J:79569
Biological Process	GO:0001779	natural killer cell differentiation	IMP	J:119213
Biological Process	GO:0071866	negative regulation of apoptotic process in bone marrow cell	IGI	J:166692
Biological Process	GO:0045787	positive regulation of cell cycle	IDA	J:166692
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0008284	positive regulation of cell population proliferation	IDA	J:16458
Biological Process	GO:0071864	positive regulation of cell proliferation in bone marrow	IGI	J:166692
Biological Process	GO:0071864	positive regulation of cell proliferation in bone marrow	IGI	J:166692
Biological Process	GO:0045663	positive regulation of myoblast differentiation	IMP	J:204300
Biological Process	GO:1901741	positive regulation of myoblast fusion	IMP	J:204300
Biological Process	GO:0032825	positive regulation of natural killer cell differentiation	IMP	J:119213
Biological Process	GO:0032819	positive regulation of natural killer cell proliferation	ISO	J:155856
Biological Process	GO:0090290	positive regulation of osteoclast proliferation	IGI	J:166692
Biological Process	GO:0090290	positive regulation of osteoclast proliferation	IDA	J:166692
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IGI	J:162445
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IGI	J:162445
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:166692
Biological Process	GO:0006468	protein phosphorylation	IGI	J:162445
Biological Process	GO:0006468	protein phosphorylation	IGI	J:162445
Biological Process	GO:0030885	regulation of myeloid dendritic cell activation	IMP	J:208234