GO Annotations Graph

• Symbol: Fst
• Name: follistatin
• ID: MGI:95586

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0048185	activin binding	ISO	J:164563
Molecular Function	GO:0048185	activin binding	IBA	J:265628
Molecular Function	GO:0038102	activin receptor antagonist activity	ISO	J:164563
Molecular Function	GO:0043395	heparan sulfate proteoglycan binding	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:168179
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:168179
Biological Process	GO:0036305	ameloblast differentiation	IMP	J:94518
Biological Process	GO:0036305	ameloblast differentiation	IGI	J:94518
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:94518
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0008585	female gonad development	IMP	J:90277
Biological Process	GO:0007276	gamete generation	IGI	J:90277
Biological Process	GO:0031069	hair follicle morphogenesis	IMP	J:118511
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	ISO	J:164563
Biological Process	GO:0043616	keratinocyte proliferation	IMP	J:118511
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	IBA	J:265628
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	IMP	J:94518
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	IGI	J:94518
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:91704
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:94518
Biological Process	GO:0007389	pattern specification process	IMP	J:94518
Biological Process	GO:0051798	positive regulation of hair follicle development	ISO	J:118511
Biological Process	GO:0030510	regulation of BMP signaling pathway	IBA	J:265628
Biological Process	GO:0001501	skeletal system development	IGI	J:201148