GO Annotations Graph

• Symbol: Gabra5
• Name: gamma-aminobutyric acid type A receptor subunit alpha 5
• ID: MGI:95617

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008503	benzodiazepine receptor activity	IBA	J:265628
Molecular Function	GO:0005254	chloride channel activity	IEA	J:60000
Molecular Function	GO:0005230	extracellular ligand-gated monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0050811	GABA receptor binding	ISO	J:155856
Molecular Function	GO:0004890	GABA-A receptor activity	ISO	J:155856
Molecular Function	GO:0004890	GABA-A receptor activity	IBA	J:265628
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	IBA	J:265628
Molecular Function	GO:0005237	inhibitory extracellular ligand-gated monoatomic ion channel activity	IBA	J:265628
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO	J:164563
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:200297
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	ISO	J:155856
Cellular Component	GO:0044297	cell body	IDA	J:107941
Cellular Component	GO:0034707	chloride channel complex	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IDA	J:107941
Cellular Component	GO:0032590	dendrite membrane	IBA	J:265628
Cellular Component	GO:1902711	GABA-A receptor complex	IBA	J:265628
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0032809	neuronal cell body membrane	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0098794	postsynapse	IBA	J:265628
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0099634	postsynaptic specialization membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	ISO	J:155856
Cellular Component	GO:0045202	synapse	IBA	J:265628
Biological Process	GO:0008306	associative learning	IMP	J:77343
Biological Process	GO:0001662	behavioral fear response	IMP	J:77343
Biological Process	GO:0007268	chemical synaptic transmission	ISO	J:155856
Biological Process	GO:1902476	chloride transmembrane transport	IBA	J:265628
Biological Process	GO:0006821	chloride transport	IEA	J:72247
Biological Process	GO:0006821	chloride transport	IEA	J:60000
Biological Process	GO:0090102	cochlea development	IMP	J:112951
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	IBA	J:265628
Biological Process	GO:0060119	inner ear receptor cell development	IMP	J:112951
Biological Process	GO:0060384	innervation	IMP	J:112951
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:112951
Biological Process	GO:0050877	nervous system process	IBA	J:265628
Biological Process	GO:0048666	neuron development	IMP	J:112951
Biological Process	GO:0043523	regulation of neuron apoptotic process	IMP	J:112951
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	IBA	J:265628
Biological Process	GO:0007605	sensory perception of sound	IMP	J:112951
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0051932	synaptic transmission, GABAergic	IBA	J:265628