GO Annotations Graph

• Symbol: Gabrb1
• Name: gamma-aminobutyric acid type A receptor subunit beta 1
• ID: MGI:95619

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005254	chloride channel activity	IEA	J:60000
Molecular Function	GO:0005230	extracellular ligand-gated monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0150047	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	IMP	J:70558
Molecular Function	GO:0150047	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	EXP	J:70558
Molecular Function	GO:0150047	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	IMP	J:70558
Molecular Function	GO:0150047	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	IDA	J:70558
Molecular Function	GO:0150047	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	IDA	J:70558
Molecular Function	GO:0150047	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	EXP	J:70558
Molecular Function	GO:0050811	GABA receptor binding	ISO	J:155856
Molecular Function	GO:0004890	GABA-A receptor activity	ISO	J:155856
Molecular Function	GO:0004890	GABA-A receptor activity	IBA	J:265628
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	ISO	J:164563
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	ISO	J:155856
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO	J:164563
Molecular Function	GO:0005253	monoatomic anion channel activity	ISO	J:155856
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0030594	neurotransmitter receptor activity	IBA	J:265628
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	ISO	J:155856
Cellular Component	GO:0034707	chloride channel complex	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:1902711	GABA-A receptor complex	ISO	J:164563
Cellular Component	GO:1902711	GABA-A receptor complex	ISO	J:155856
Cellular Component	GO:1902711	GABA-A receptor complex	IBA	J:265628
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:70558
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:70558
Cellular Component	GO:0098982	GABA-ergic synapse	EXP	J:70558
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0005635	nuclear envelope	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IEA	J:60000
Cellular Component	GO:0099634	postsynaptic specialization membrane	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IC	J:70558
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:70558
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	EXP	J:70558
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:70558
Cellular Component	GO:0045202	synapse	IBA	J:265628
Biological Process	GO:0071420	cellular response to histamine	ISO	J:155856
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:1902476	chloride transmembrane transport	ISO	J:164563
Biological Process	GO:0006821	chloride transport	IEA	J:60000
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	EXP	J:70558
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	ISO	J:164563
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	ISO	J:155856
Biological Process	GO:0050877	nervous system process	IBA	J:265628
Biological Process	GO:0042391	regulation of membrane potential	IBA	J:265628
Biological Process	GO:0099505	regulation of presynaptic membrane potential	EXP	J:70558
Biological Process	GO:0009636	response to toxic substance	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IBA	J:265628