GO Annotations Graph

• Symbol: Gas6
• Name: growth arrest specific 6
• ID: MGI:95660

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0001786	phosphatidylserine binding	ISO	J:164563
Molecular Function	GO:0030296	protein tyrosine kinase activator activity	ISO	J:164563
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ISO	J:164563
Molecular Function	GO:0048018	receptor ligand activity	IBA	J:265628
Molecular Function	GO:0048018	receptor ligand activity	IDA	J:44193
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:73065
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IDA	J:131177
Cellular Component	GO:0005615	extracellular space	ISO	J:63534
Biological Process	GO:0032148	activation of protein kinase B activity	ISO	J:155856
Biological Process	GO:0043277	apoptotic cell clearance	ISO	J:164563
Biological Process	GO:0043277	apoptotic cell clearance	IDA	J:133455
Biological Process	GO:0006915	apoptotic process	IMP	J:90648
Biological Process	GO:0035754	B cell chemotaxis	ISO	J:164563
Biological Process	GO:0007596	blood coagulation	IMP	J:90648
Biological Process	GO:0070588	calcium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0031589	cell-substrate adhesion	IMP	J:131177
Biological Process	GO:0071333	cellular response to glucose stimulus	ISO	J:155856
Biological Process	GO:0071363	cellular response to growth factor stimulus	IDA	J:63534
Biological Process	GO:0071363	cellular response to growth factor stimulus	IMP	J:131177
Biological Process	GO:0035457	cellular response to interferon-alpha	ISO	J:164563
Biological Process	GO:0009267	cellular response to starvation	IDA	J:63534
Biological Process	GO:0071307	cellular response to vitamin K	ISO	J:164563
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	ISO	J:164563
Biological Process	GO:0007167	enzyme-linked receptor protein signaling pathway	IGI	J:44193
Biological Process	GO:0044346	fibroblast apoptotic process	IMP	J:90648
Biological Process	GO:0019064	fusion of virus membrane with host plasma membrane	ISO	J:164563
Biological Process	GO:0097241	hematopoietic stem cell migration to bone marrow	ISO	J:164563
Biological Process	GO:0010934	macrophage cytokine production	IMP	J:131177
Biological Process	GO:0033028	myeloid cell apoptotic process	IMP	J:131177
Biological Process	GO:0043066	negative regulation of apoptotic process	IDA	J:182390
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IDA	J:44193
Biological Process	GO:0043066	negative regulation of apoptotic process	IGI	J:44193
Biological Process	GO:0070168	negative regulation of biomineral tissue development	ISO	J:164563
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:2000669	negative regulation of dendritic cell apoptotic process	ISO	J:164563
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	ISO	J:164563
Biological Process	GO:2000270	negative regulation of fibroblast apoptotic process	ISO	J:164563
Biological Process	GO:2000270	negative regulation of fibroblast apoptotic process	IMP	J:90648
Biological Process	GO:0032692	negative regulation of interleukin-1 production	ISO	J:164563
Biological Process	GO:0032715	negative regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:0033033	negative regulation of myeloid cell apoptotic process	IMP	J:131177
Biological Process	GO:1900142	negative regulation of oligodendrocyte apoptotic process	ISO	J:164563
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0032689	negative regulation of type II interferon production	ISO	J:164563
Biological Process	GO:0001764	neuron migration	IGI	J:141251
Biological Process	GO:0018105	peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0006909	phagocytosis	ISO	J:164563
Biological Process	GO:0001961	positive regulation of cytokine-mediated signaling pathway	ISO	J:164563
Biological Process	GO:2000510	positive regulation of dendritic cell chemotaxis	ISO	J:164563
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:73065
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	ISO	J:73065
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0003104	positive regulation of glomerular filtration	ISO	J:155856
Biological Process	GO:0032825	positive regulation of natural killer cell differentiation	ISO	J:164563
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0050766	positive regulation of phagocytosis	ISO	J:164563
Biological Process	GO:0046827	positive regulation of protein export from nucleus	ISO	J:164563
Biological Process	GO:0045860	positive regulation of protein kinase activity	ISO	J:164563
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ISO	J:155856
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	ISO	J:164563
Biological Process	GO:0032008	positive regulation of TOR signaling	ISO	J:155856
Biological Process	GO:0043491	protein kinase B signaling	ISO	J:164563
Biological Process	GO:0043491	protein kinase B signaling	IBA	J:265628
Biological Process	GO:0043491	protein kinase B signaling	IMP	J:131177
Biological Process	GO:0043491	protein kinase B signaling	IGI	J:95952
Biological Process	GO:0043491	protein kinase B signaling	IGI	J:95952
Biological Process	GO:0043491	protein kinase B signaling	IGI	J:95952
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0046813	receptor-mediated virion attachment to host cell	ISO	J:164563
Biological Process	GO:0040008	regulation of growth	IEA	J:60000
Biological Process	GO:0007165	signal transduction	ISO	J:155856
Biological Process	GO:0007165	signal transduction	ISO	J:164563
Biological Process	GO:0046718	viral entry into host cell	ISO	J:164563
Biological Process	GO:0019079	viral genome replication	ISO	J:164563