Gata4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Gata4
GATA binding protein 4
MGI:95664

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:171727
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0070410	co-SMAD binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	ISO	J:73065
Molecular Function	GO:0003677	DNA binding	IDA	J:19374
Molecular Function	GO:0003677	DNA binding	IDA	J:50069
Molecular Function	GO:0001216	DNA-binding transcription activator activity	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:50069
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:91550
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:127378
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:113930
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:196264
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:124791
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:171727
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:108520
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0051525	NFAT protein binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:95125
Molecular Function	GO:0005515	protein binding	IPI	J:203454
Molecular Function	GO:0005515	protein binding	IPI	J:175199
Molecular Function	GO:0005515	protein binding	IPI	J:124772
Molecular Function	GO:0005515	protein binding	IPI	J:166035
Molecular Function	GO:0005515	protein binding	IPI	J:113930
Molecular Function	GO:0005515	protein binding	IPI	J:180125
Molecular Function	GO:0005515	protein binding	IPI	J:108520
Molecular Function	GO:0005515	protein binding	IPI	J:124791
Molecular Function	GO:0005515	protein binding	IPI	J:94180
Molecular Function	GO:0005515	protein binding	IPI	J:164279
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:196264
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:96456
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:108520
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:155856
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:241318
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:34383
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:4641
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:155856
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:47815
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:47815
Molecular Function	GO:0001223	transcription coactivator binding	IPI	J:74328
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0000785	chromatin	IDA	J:196264
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9690868
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9692157
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9692234
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9759884
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9759916
Cellular Component	GO:0005634	nucleus	IDA	J:168242
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:127378
Cellular Component	GO:0005634	nucleus	IDA	J:206154
Cellular Component	GO:0005634	nucleus	IDA	J:156932
Cellular Component	GO:0005634	nucleus	IDA	J:124791
Cellular Component	GO:0005634	nucleus	ISO	J:47815
Cellular Component	GO:0005634	nucleus	ISO	J:47815
Cellular Component	GO:0005634	nucleus	IDA	J:170416
Cellular Component	GO:0005634	nucleus	IDA	J:85611
Cellular Component	GO:0005634	nucleus	IDA	J:117570
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Biological Process	GO:0003180	aortic valve morphogenesis	ISO	J:164563
Biological Process	GO:0060413	atrial septum morphogenesis	ISO	J:164563
Biological Process	GO:0003289	atrial septum primum morphogenesis	IMP	J:129483
Biological Process	GO:0003290	atrial septum secundum morphogenesis	ISO	J:164563
Biological Process	GO:0036302	atrioventricular canal development	IGI	J:170471
Biological Process	GO:0003190	atrioventricular valve formation	IGI	J:170471
Biological Process	GO:0003181	atrioventricular valve morphogenesis	TAS	J:99745
Biological Process	GO:0003181	atrioventricular valve morphogenesis	IGI	J:145175
Biological Process	GO:0055007	cardiac muscle cell differentiation	NAS	J:173154
Biological Process	GO:0055007	cardiac muscle cell differentiation	IGI	J:167933
Biological Process	GO:0055007	cardiac muscle cell differentiation	IGI	J:167933
Biological Process	GO:0055007	cardiac muscle cell differentiation	IGI	J:135185
Biological Process	GO:0055007	cardiac muscle cell differentiation	IMP	J:135185
Biological Process	GO:0055007	cardiac muscle cell differentiation	IGI	J:135185
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:145175
Biological Process	GO:0014898	cardiac muscle hypertrophy in response to stress	IMP	J:171966
Biological Process	GO:0048738	cardiac muscle tissue development	IGI	J:171966
Biological Process	GO:0061026	cardiac muscle tissue regeneration	IDA	J:232979
Biological Process	GO:0003215	cardiac right ventricle morphogenesis	IMP	J:129483
Biological Process	GO:0003279	cardiac septum development	IGI	J:170471
Biological Process	GO:0045165	cell fate commitment	IBA	J:265628
Biological Process	GO:0061049	cell growth involved in cardiac muscle cell development	ISO	J:155856
Biological Process	GO:0007267	cell-cell signaling	IMP	J:101033
Biological Process	GO:0007267	cell-cell signaling	IMP	J:101033
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	IDA	J:42411
Biological Process	GO:0071371	cellular response to gonadotropin stimulus	IDA	J:42411
Biological Process	GO:0060540	diaphragm morphogenesis	TAS	J:129483
Biological Process	GO:0048557	embryonic digestive tract morphogenesis	IMP	J:101033
Biological Process	GO:0048617	embryonic foregut morphogenesis	IMP	J:40144
Biological Process	GO:0048617	embryonic foregut morphogenesis	IMP	J:40145
Biological Process	GO:0035054	embryonic heart tube anterior/posterior pattern specification	IMP	J:40144
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:40144
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:40145
Biological Process	GO:0048598	embryonic morphogenesis	IMP	J:40145
Biological Process	GO:0048598	embryonic morphogenesis	IMP	J:40144
Biological Process	GO:0003197	endocardial cushion development	IMP	J:129483
Biological Process	GO:0003197	endocardial cushion development	ISO	J:164563
Biological Process	GO:0003197	endocardial cushion development	IGI	J:145175
Biological Process	GO:0001706	endoderm formation	IMP	J:29883
Biological Process	GO:0072148	epithelial cell fate commitment	IMP	J:117570
Biological Process	GO:0001702	gastrulation with mouth forming second	IMP	J:40145
Biological Process	GO:0007507	heart development	IMP	J:94637
Biological Process	GO:0007507	heart development	IMP	J:94637
Biological Process	GO:0007507	heart development	IMP	J:94637
Biological Process	GO:0007507	heart development	IMP	J:94637
Biological Process	GO:0007507	heart development	IMP	J:77392
Biological Process	GO:0007507	heart development	IMP	J:94637
Biological Process	GO:0007507	heart development	IMP	J:94637
Biological Process	GO:0007507	heart development	IMP	J:94637
Biological Process	GO:0007507	heart development	IMP	J:94637
Biological Process	GO:0007507	heart development	IMP	J:94637
Biological Process	GO:0007507	heart development	IMP	J:94637
Biological Process	GO:0007507	heart development	IMP	J:94637
Biological Process	GO:0007507	heart development	IMP	J:94637
Biological Process	GO:0001947	heart looping	IMP	J:92434
Biological Process	GO:0003007	heart morphogenesis	IMP	J:127378
Biological Process	GO:0001701	in utero embryonic development	IMP	J:40144
Biological Process	GO:0001701	in utero embryonic development	IMP	J:92434
Biological Process	GO:0001701	in utero embryonic development	IMP	J:40145
Biological Process	GO:0001701	in utero embryonic development	IMP	J:156932
Biological Process	GO:0060575	intestinal epithelial cell differentiation	ISO	J:47815
Biological Process	GO:0060464	lung lobe formation	IMP	J:134027
Biological Process	GO:0060425	lung morphogenesis	TAS	J:129483
Biological Process	GO:0008584	male gonad development	ISO	J:164563
Biological Process	GO:0003192	mitral valve formation	TAS	J:99745
Biological Process	GO:0043066	negative regulation of apoptotic process	IDA	J:242464
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	IDA	J:232979
Biological Process	GO:0010507	negative regulation of autophagy	ISO	J:155856
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptotic process	IGI	J:232979
Biological Process	GO:1905204	negative regulation of connective tissue replacement	IDA	J:232979
Biological Process	GO:0010629	negative regulation of gene expression	IDA	J:232979
Biological Process	GO:0010629	negative regulation of gene expression	IDA	J:232979
Biological Process	GO:1903202	negative regulation of oxidative stress-induced cell death	IDA	J:232979
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0003151	outflow tract morphogenesis	TAS	J:99745
Biological Process	GO:0045766	positive regulation of angiogenesis	IDA	J:127378
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	ISO	J:155856
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IGI	J:145175
Biological Process	GO:0045787	positive regulation of cell cycle	IDA	J:242464
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:113930
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:127378
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:89500
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IDA	J:232979
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:242464
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:232979
Biological Process	GO:0010628	positive regulation of gene expression	TAS	J:241318
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IDA	J:232979
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:168242
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:113930
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:196264
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:4641
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:124791
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:47815
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:96456
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:105332
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:96456
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:19374
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:96456
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:122635
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	IDA	J:127378
Biological Process	GO:0086004	regulation of cardiac muscle cell contraction	ISO	J:155856
Biological Process	GO:0060043	regulation of cardiac muscle cell proliferation	IMP	J:99203
Biological Process	GO:0006355	regulation of DNA-templated transcription	TAS	J:169941
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:50069
Biological Process	GO:0010468	regulation of gene expression	IGI	J:135185
Biological Process	GO:0010468	regulation of gene expression	IGI	J:135185
Biological Process	GO:0010468	regulation of gene expression	IGI	J:135185
Biological Process	GO:0010468	regulation of gene expression	IGI	J:135185
Biological Process	GO:0010468	regulation of gene expression	IGI	J:135185
Biological Process	GO:0010468	regulation of gene expression	IGI	J:135185
Biological Process	GO:0010468	regulation of gene expression	IGI	J:135185
Biological Process	GO:0010468	regulation of gene expression	IDA	J:164279
Biological Process	GO:0010468	regulation of gene expression	IGI	J:135185
Biological Process	GO:0010468	regulation of gene expression	IGI	J:135185
Biological Process	GO:0010468	regulation of gene expression	IGI	J:135185
Biological Process	GO:0051896	regulation of protein kinase B signaling	IDA	J:232979
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:91550
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:4641
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:89500
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:19374
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:82545
Biological Process	GO:0043627	response to estrogen	IDA	J:42411
Biological Process	GO:0009612	response to mechanical stimulus	ISO	J:155856
Biological Process	GO:0032526	response to retinoic acid	IDA	J:137480
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:164563
Biological Process	GO:0072520	seminiferous tubule development	IMP	J:169018
Biological Process	GO:0060008	Sertoli cell differentiation	IMP	J:169018
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IDA	J:155850
Biological Process	GO:0035914	skeletal muscle cell differentiation	NAS	J:173154
Biological Process	GO:0060395	SMAD protein signal transduction	IDA	J:45399
Biological Process	GO:0007283	spermatogenesis	IMP	J:169018
Biological Process	GO:0060290	transdifferentiation	ISO	J:155856
Biological Process	GO:0003195	tricuspid valve formation	TAS	J:99745
Biological Process	GO:0035239	tube morphogenesis	IGI	J:135185
Biological Process	GO:0060979	vasculogenesis involved in coronary vascular morphogenesis	TAS	J:169941
Biological Process	GO:0003229	ventricular cardiac muscle tissue development	IGI	J:145175
Biological Process	GO:0003281	ventricular septum development	IMP	J:129483
Biological Process	GO:0042060	wound healing	IDA	J:232979

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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