GO Annotations Graph

• Symbol: Gbx2
• Name: gastrulation brain homeobox 2
• ID: MGI:95668

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:195357
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	IDA	J:195357
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:195357
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:195357
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:195357
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:195357
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IDA	J:195357
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:195357
Biological Process	GO:0048483	autonomic nervous system development	IMP	J:100584
Biological Process	GO:0048483	autonomic nervous system development	IMP	J:100584
Biological Process	GO:0048483	autonomic nervous system development	IMP	J:100584
Biological Process	GO:0007411	axon guidance	IMP	J:76341
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IGI	J:100584
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IGI	J:100584
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IMP	J:100584
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IMP	J:100584
Biological Process	GO:0021930	cerebellar granule cell precursor proliferation	IMP	J:108519
Biological Process	GO:0021930	cerebellar granule cell precursor proliferation	IMP	J:108519
Biological Process	GO:0021549	cerebellum development	IMP	J:108519
Biological Process	GO:0021549	cerebellum development	IMP	J:108519
Biological Process	GO:0021884	forebrain neuron development	IMP	J:166699
Biological Process	GO:0030902	hindbrain development	IMP	J:98487
Biological Process	GO:0030902	hindbrain development	IMP	J:98487
Biological Process	GO:0030902	hindbrain development	IMP	J:98487
Biological Process	GO:0030902	hindbrain development	IMP	J:108519
Biological Process	GO:0030902	hindbrain development	IMP	J:98487
Biological Process	GO:0030902	hindbrain development	IMP	J:98487
Biological Process	GO:0030902	hindbrain development	IMP	J:98487
Biological Process	GO:0030902	hindbrain development	IMP	J:108519
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:100584
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:98487
Biological Process	GO:0030917	midbrain-hindbrain boundary development	IMP	J:108519
Biological Process	GO:0021555	midbrain-hindbrain boundary morphogenesis	IMP	J:108519
Biological Process	GO:0001755	neural crest cell migration	IMP	J:100584
Biological Process	GO:0001755	neural crest cell migration	IMP	J:195357
Biological Process	GO:0001755	neural crest cell migration	IMP	J:152319
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:195357
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0051960	regulation of nervous system development	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0021568	rhombomere 2 development	IMP	J:108519
Biological Process	GO:0021794	thalamus development	IMP	J:147282
Biological Process	GO:0035239	tube morphogenesis	IMP	J:100584