GO Annotations Graph

• Symbol: Ggt1
• Name: gamma-glutamyltransferase 1
• ID: MGI:95706

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016746	acyltransferase activity	IEA	J:60000
Molecular Function	GO:0016755	aminoacyltransferase activity	ISO	J:155856
Molecular Function	GO:0036374	glutathione hydrolase activity	ISS	J:242467
Molecular Function	GO:0036374	glutathione hydrolase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0102953	hypoglycin A gamma-glutamyl transpeptidase activity	IEA	J:72245
Molecular Function	GO:0103068	leukotriene C4 gamma-glutamyl transferase activity	IEA	J:72245
Molecular Function	GO:0002951	leukotriene-C(4) hydrolase	ISO	J:164563
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0000048	peptidyltransferase activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	TAS	J:30648
Cellular Component	GO:0031982	vesicle	IDA	J:200928
Biological Process	GO:0019344	cysteine biosynthetic process	IMP	J:177168
Biological Process	GO:0006750	glutathione biosynthetic process	IMP	J:177168
Biological Process	GO:0006751	glutathione catabolic process	IBA	J:265628
Biological Process	GO:0006749	glutathione metabolic process	TAS	J:30648
Biological Process	GO:0031179	peptide modification	ISO	J:155856
Biological Process	GO:0031179	peptide modification	IBA	J:265628
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0002682	regulation of immune system process	IMP	J:177168
Biological Process	GO:0002682	regulation of immune system process	IBA	J:265628
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:177168
Biological Process	GO:0050727	regulation of inflammatory response	IBA	J:265628
Biological Process	GO:0007283	spermatogenesis	IMP	J:55222