GO Annotations Graph

• Symbol: Ghrhr
• Name: growth hormone releasing hormone receptor
• ID: MGI:95710

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008528	G protein-coupled peptide receptor activity	IBA	J:265628
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0019838	growth factor binding	ISO	J:164563
Molecular Function	GO:0019838	growth factor binding	IBA	J:265628
Molecular Function	GO:0016520	growth hormone-releasing hormone receptor activity	ISO	J:155856
Molecular Function	GO:0016520	growth hormone-releasing hormone receptor activity	ISO	J:164563
Molecular Function	GO:0016520	growth hormone-releasing hormone receptor activity	IBA	J:265628
Molecular Function	GO:0016520	growth hormone-releasing hormone receptor activity	IGI	J:13404
Molecular Function	GO:0016520	growth hormone-releasing hormone receptor activity	IMP	J:58346
Molecular Function	GO:0017046	peptide hormone binding	IPI	J:145213
Molecular Function	GO:0017046	peptide hormone binding	ISO	J:164563
Molecular Function	GO:0017046	peptide hormone binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:58346
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:58346
Cellular Component	GO:0016020	membrane	ISO	J:73065
Cellular Component	GO:0005637	nuclear inner membrane	ISO	J:164563
Cellular Component	GO:0016363	nuclear matrix	ISO	J:164563
Cellular Component	GO:0005640	nuclear outer membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:58346
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Cellular Component	GO:0030141	secretory granule	ISO	J:164563
Biological Process	GO:0007190	activation of adenylate cyclase activity	ISO	J:155856
Biological Process	GO:0021984	adenohypophysis development	IMP	J:5647
Biological Process	GO:0021984	adenohypophysis development	IMP	J:15586
Biological Process	GO:0021984	adenohypophysis development	IMP	J:3198
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IGI	J:13404
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IGI	J:33102
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IMP	J:8252
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IMP	J:58346
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IGI	J:12846
Biological Process	GO:0019933	cAMP-mediated signaling	ISO	J:155856
Biological Process	GO:0019933	cAMP-mediated signaling	ISO	J:164563
Biological Process	GO:0048469	cell maturation	IMP	J:802
Biological Process	GO:0007166	cell surface receptor signaling pathway	IEA	J:72247
Biological Process	GO:0032869	cellular response to insulin stimulus	IDA	J:129482
Biological Process	GO:0008340	determination of adult lifespan	IMP	J:69878
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:8252
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0030252	growth hormone secretion	IMP	J:8252
Biological Process	GO:0030252	growth hormone secretion	IMP	J:8252
Biological Process	GO:0042445	hormone metabolic process	IMP	J:5647
Biological Process	GO:0042445	hormone metabolic process	IMP	J:5647
Biological Process	GO:0046879	hormone secretion	IMP	J:3735
Biological Process	GO:0007595	lactation	IMP	J:5647
Biological Process	GO:0007595	lactation	IMP	J:802
Biological Process	GO:0030879	mammary gland development	IMP	J:105630
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:145213
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	ISO	J:155856
Biological Process	GO:0060124	positive regulation of growth hormone secretion	ISO	J:155856
Biological Process	GO:0060124	positive regulation of growth hormone secretion	IMP	J:7060
Biological Process	GO:0060124	positive regulation of growth hormone secretion	IMP	J:5710
Biological Process	GO:0060124	positive regulation of growth hormone secretion	IMP	J:8252
Biological Process	GO:0046887	positive regulation of hormone secretion	IMP	J:3735
Biological Process	GO:0040018	positive regulation of multicellular organism growth	ISO	J:164563
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:1793
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:3735
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IGI	J:95918
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:60661
Biological Process	GO:0040018	positive regulation of multicellular organism growth	ISO	J:73065
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:5647
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:95918
Biological Process	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	IMP	J:6340
Biological Process	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	IMP	J:3735
Biological Process	GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	IMP	J:56310
Biological Process	GO:0051246	regulation of protein metabolic process	IGI	J:16863
Biological Process	GO:0043627	response to estrogen	ISO	J:164563
Biological Process	GO:0051384	response to glucocorticoid	ISO	J:164563
Biological Process	GO:0032868	response to insulin	ISO	J:164563
Biological Process	GO:0007165	signal transduction	ISO	J:155856
Biological Process	GO:0060133	somatotropin secreting cell development	IMP	J:7211
Biological Process	GO:0060133	somatotropin secreting cell development	IMP	J:15348