GO Annotations Graph

• Symbol: Gli1
• Name: GLI-Kruppel family member GLI1
• ID: MGI:95727

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IDA	J:104380
Molecular Function	GO:0003682	chromatin binding	IDA	J:104380
Molecular Function	GO:0003682	chromatin binding	IDA	J:121411
Molecular Function	GO:0003682	chromatin binding	IDA	J:104380
Molecular Function	GO:0003682	chromatin binding	IDA	J:104380
Molecular Function	GO:0003677	DNA binding	ISO	J:73065
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:121411
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008017	microtubule binding	IDA	J:72866
Molecular Function	GO:0005515	protein binding	IPI	J:152551
Molecular Function	GO:0005515	protein binding	IPI	J:63778
Molecular Function	GO:0005515	protein binding	IPI	J:58014
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:201786
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:95234
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:73065
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Cellular Component	GO:0005930	axoneme	IDA	J:115756
Cellular Component	GO:0005929	cilium	IDA	J:115756
Cellular Component	GO:0005929	cilium	IDA	J:151923
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:151923
Cellular Component	GO:0005737	cytoplasm	IDA	J:105822
Cellular Component	GO:0005737	cytoplasm	IDA	J:72866
Cellular Component	GO:0005737	cytoplasm	IGI	J:103171
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:1990788	GLI-SUFU complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:106653
Cellular Component	GO:0005634	nucleus	IDA	J:151923
Cellular Component	GO:0005634	nucleus	IDA	J:121411
Cellular Component	GO:0005634	nucleus	IDA	J:115756
Cellular Component	GO:0005634	nucleus	IDA	J:72866
Cellular Component	GO:0005634	nucleus	IDA	J:103171
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0021696	cerebellar cortex morphogenesis	IGI	J:108507
Biological Process	GO:0009953	dorsal/ventral pattern formation	IGI	J:106158
Biological Process	GO:0009913	epidermal cell differentiation	ISO	J:164563
Biological Process	GO:0097421	liver regeneration	IMP	J:201786
Biological Process	GO:0030324	lung development	IGI	J:60986
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:1990787	negative regulation of hh target transcription factor activity	ISO	J:164563
Biological Process	GO:0060032	notochord regression	IGI	J:60986
Biological Process	GO:0001649	osteoblast differentiation	ISO	J:164563
Biological Process	GO:0021983	pituitary gland development	IGI	J:60986
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	ISO	J:164563
Biological Process	GO:1902808	positive regulation of cell cycle G1/S phase transition	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045740	positive regulation of DNA replication	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:164782
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:115756
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:95234
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:112463
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:108433
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:201786
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:121411
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:121411
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:121411
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:121411
Biological Process	GO:0009954	proximal/distal pattern formation	IGI	J:106158
Biological Process	GO:2000345	regulation of hepatocyte proliferation	IMP	J:201786
Biological Process	GO:0045667	regulation of osteoblast differentiation	IMP	J:185618
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0009611	response to wounding	IMP	J:201786
Biological Process	GO:0009611	response to wounding	IDA	J:201786
Biological Process	GO:0007165	signal transduction	TAS	J:72866
Biological Process	GO:0007224	smoothened signaling pathway	ISO	J:164563
Biological Process	GO:0007224	smoothened signaling pathway	IBA	J:265628
Biological Process	GO:0007224	smoothened signaling pathway	IDA	J:192563
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:135198
Biological Process	GO:0007224	smoothened signaling pathway	IDA	J:146198
Biological Process	GO:0007224	smoothened signaling pathway	IDA	J:50462
Biological Process	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	IGI	J:108507
Biological Process	GO:0007283	spermatogenesis	IDA	J:72866
Biological Process	GO:0007418	ventral midline development	IGI	J:60986