Gli3 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Gli3
GLI-Kruppel family member GLI3
MGI:95729

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IGI	J:104380
Molecular Function	GO:0003682	chromatin binding	IGI	J:104380
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:169807
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0035035	histone acetyltransferase binding	ISO	J:164563
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0036033	mediator complex binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:152259
Molecular Function	GO:0005515	protein binding	IPI	J:149459
Molecular Function	GO:0005515	protein binding	IPI	J:257035
Molecular Function	GO:0005515	protein binding	IPI	J:158961
Molecular Function	GO:0005515	protein binding	IPI	J:151923
Molecular Function	GO:0005515	protein binding	IPI	J:80205
Molecular Function	GO:0005515	protein binding	IPI	J:207249
Molecular Function	GO:0005515	protein binding	IPI	J:63778
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:73065
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:73065
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:108433
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005930	axoneme	IDA	J:168317
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005929	cilium	IDA	J:168317
Cellular Component	GO:0005929	cilium	ISO	J:164563
Cellular Component	GO:0005929	cilium	IDA	J:232111
Cellular Component	GO:0005929	cilium	ISO	J:115756
Cellular Component	GO:0005929	cilium	IDA	J:260445
Cellular Component	GO:0005929	cilium	IDA	J:151923
Cellular Component	GO:0005929	cilium	IDA	J:182871
Cellular Component	GO:0005929	cilium	IDA	J:212094
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:158961
Cellular Component	GO:0005737	cytoplasm	IDA	J:151923
Cellular Component	GO:0005737	cytoplasm	IDA	J:80205
Cellular Component	GO:0005737	cytoplasm	IDA	J:207249
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:1990788	GLI-SUFU complex	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016607	nuclear speck	IDA	J:151923
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9008236
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:158961
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:151923
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IDA	J:207249
Cellular Component	GO:0005634	nucleus	ISO	J:115756
Cellular Component	GO:0005634	nucleus	IDA	J:80205
Cellular Component	GO:0017053	transcription repressor complex	IDA	J:80205
Biological Process	GO:0046632	alpha-beta T cell differentiation	IMP	J:117284
Biological Process	GO:0048856	anatomical structure development	IGI	J:70870
Biological Process	GO:0048856	anatomical structure development	IGI	J:70870
Biological Process	GO:0048856	anatomical structure development	IGI	J:70870
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IGI	J:49603
Biological Process	GO:0060873	anterior semicircular canal development	IMP	J:121232
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:92507
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:188038
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:188038
Biological Process	GO:0006915	apoptotic process	IMP	J:145009
Biological Process	GO:0060840	artery development	IGI	J:119563
Biological Process	GO:0007411	axon guidance	IMP	J:165487
Biological Process	GO:0007411	axon guidance	IMP	J:109287
Biological Process	GO:0007411	axon guidance	IMP	J:165487
Biological Process	GO:0007420	brain development	IMP	J:17581
Biological Process	GO:0007420	brain development	IMP	J:80177
Biological Process	GO:0007420	brain development	IMP	J:121232
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IGI	J:104380
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	IMP	J:102853
Biological Process	GO:0043010	camera-type eye development	IGI	J:139168
Biological Process	GO:0048593	camera-type eye morphogenesis	IMP	J:4086
Biological Process	GO:0061005	cell differentiation involved in kidney development	IGI	J:154102
Biological Process	GO:0008283	cell population proliferation	IMP	J:163175
Biological Process	GO:0008283	cell population proliferation	IMP	J:104380
Biological Process	GO:0008283	cell population proliferation	IGI	J:104380
Biological Process	GO:0008283	cell population proliferation	IGI	J:104380
Biological Process	GO:0008283	cell population proliferation	IGI	J:163175
Biological Process	GO:0008283	cell population proliferation	IMP	J:104380
Biological Process	GO:0007417	central nervous system development	IGI	J:80206
Biological Process	GO:0007417	central nervous system development	IMP	J:80207
Biological Process	GO:0021801	cerebral cortex radial glia-guided migration	IMP	J:43330
Biological Process	GO:0002062	chondrocyte differentiation	IGI	J:102948
Biological Process	GO:0048589	developmental growth	IMP	J:42454
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:108509
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:80207
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:108509
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:87948
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:80207
Biological Process	GO:0048566	embryonic digestive tract development	IMP	J:60446
Biological Process	GO:0048557	embryonic digestive tract morphogenesis	IMP	J:102853
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:115756
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:142500
Biological Process	GO:0042733	embryonic digit morphogenesis	IGI	J:42445
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:42445
Biological Process	GO:0042733	embryonic digit morphogenesis	IGI	J:128015
Biological Process	GO:0042733	embryonic digit morphogenesis	IGI	J:128015
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:188038
Biological Process	GO:0042733	embryonic digit morphogenesis	IGI	J:128015
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:4086
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:78407
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:154102
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:80205
Biological Process	GO:0030326	embryonic limb morphogenesis	IGI	J:150759
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:80177
Biological Process	GO:0030326	embryonic limb morphogenesis	IGI	J:102948
Biological Process	GO:0048598	embryonic morphogenesis	IMP	J:4086
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	IMP	J:235627
Biological Process	GO:0048568	embryonic organ development	IEA	J:72247
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IGI	J:101708
Biological Process	GO:0030900	forebrain development	IMP	J:103594
Biological Process	GO:0030900	forebrain development	IMP	J:103594
Biological Process	GO:0030900	forebrain development	IMP	J:103594
Biological Process	GO:0021798	forebrain dorsal/ventral pattern formation	IMP	J:59923
Biological Process	GO:0021861	forebrain radial glial cell differentiation	IMP	J:43330
Biological Process	GO:0060364	frontal suture morphogenesis	IMP	J:163175
Biological Process	GO:0010467	gene expression	IMP	J:192563
Biological Process	GO:0007507	heart development	IGI	J:113186
Biological Process	GO:0007442	hindgut morphogenesis	IGI	J:70870
Biological Process	GO:0021766	hippocampus development	IMP	J:203028
Biological Process	GO:0001701	in utero embryonic development	IMP	J:115756
Biological Process	GO:0048839	inner ear development	IGI	J:121232
Biological Process	GO:0001822	kidney development	IGI	J:113186
Biological Process	GO:0060366	lambdoid suture morphogenesis	IMP	J:163175
Biological Process	GO:0120223	larynx morphogenesis	IMP	J:241145
Biological Process	GO:0022018	lateral ganglionic eminence cell proliferation	IMP	J:165487
Biological Process	GO:0060875	lateral semicircular canal development	IMP	J:121232
Biological Process	GO:0021819	layer formation in cerebral cortex	IMP	J:171423
Biological Process	GO:0060173	limb development	IMP	J:121609
Biological Process	GO:0035108	limb morphogenesis	ISO	J:164563
Biological Process	GO:0035108	limb morphogenesis	IMP	J:42445
Biological Process	GO:0030324	lung development	IMP	J:42454
Biological Process	GO:0030324	lung development	IGI	J:92194
Biological Process	GO:0030879	mammary gland development	IMP	J:112460
Biological Process	GO:0030879	mammary gland development	IMP	J:112460
Biological Process	GO:0030879	mammary gland development	IMP	J:112460
Biological Process	GO:0060594	mammary gland specification	IGI	J:109476
Biological Process	GO:0030318	melanocyte differentiation	IMP	J:136642
Biological Process	GO:0001656	metanephros development	IGI	J:104380
Biological Process	GO:0046639	negative regulation of alpha-beta T cell differentiation	IMP	J:151855
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:145009
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:104380
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:104380
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:121301
Biological Process	GO:0032331	negative regulation of chondrocyte differentiation	IGI	J:102948
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:121609
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:219044
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:80205
Biological Process	GO:1990787	negative regulation of hh target transcription factor activity	ISO	J:164563
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:145009
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	IMP	J:151855
Biological Process	GO:2000647	negative regulation of stem cell proliferation	IMP	J:163175
Biological Process	GO:2000647	negative regulation of stem cell proliferation	IGI	J:163175
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0045060	negative thymic T cell selection	IMP	J:151855
Biological Process	GO:0021915	neural tube development	IMP	J:4086
Biological Process	GO:0007405	neuroblast proliferation	IMP	J:165487
Biological Process	GO:0007405	neuroblast proliferation	IMP	J:165487
Biological Process	GO:0007405	neuroblast proliferation	IMP	J:165487
Biological Process	GO:0030182	neuron differentiation	IMP	J:145009
Biological Process	GO:0048663	neuron fate commitment	IMP	J:103594
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IGI	J:49252
Biological Process	GO:0048709	oligodendrocyte differentiation	IGI	J:119850
Biological Process	GO:0021631	optic nerve morphogenesis	IMP	J:106158
Biological Process	GO:0001649	osteoblast differentiation	IMP	J:163175
Biological Process	GO:0001649	osteoblast differentiation	IGI	J:163175
Biological Process	GO:0001649	osteoblast differentiation	IMP	J:163175
Biological Process	GO:0001649	osteoblast differentiation	IGI	J:163175
Biological Process	GO:0021543	pallium development	IMP	J:53903
Biological Process	GO:0007389	pattern specification process	IGI	J:87223
Biological Process	GO:0007389	pattern specification process	IGI	J:87223
Biological Process	GO:0046638	positive regulation of alpha-beta T cell differentiation	IMP	J:117284
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	IMP	J:121301
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:169807
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:219044
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:121609
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:121301
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	IMP	J:165487
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IGI	J:163175
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IMP	J:163175
Biological Process	GO:0042307	positive regulation of protein import into nucleus	IGI	J:113403
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:151855
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006606	protein import into nucleus	IGI	J:113403
Biological Process	GO:0016485	protein processing	IDA	J:142500
Biological Process	GO:0009954	proximal/distal pattern formation	IMP	J:106158
Biological Process	GO:0009954	proximal/distal pattern formation	IGI	J:106158
Biological Process	GO:0042981	regulation of apoptotic process	IMP	J:17581
Biological Process	GO:1903010	regulation of bone development	IMP	J:188038
Biological Process	GO:0045595	regulation of cell differentiation	IGI	J:102948
Biological Process	GO:0042127	regulation of cell population proliferation	IGI	J:117221
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:39658
Biological Process	GO:0010468	regulation of gene expression	IGI	J:142755
Biological Process	GO:0010468	regulation of gene expression	IGI	J:142755
Biological Process	GO:1901620	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	IGI	J:243907
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0060021	roof of mouth development	IMP	J:139635
Biological Process	GO:0060367	sagittal suture morphogenesis	IMP	J:163175
Biological Process	GO:0007224	smoothened signaling pathway	ISO	J:164563
Biological Process	GO:0007224	smoothened signaling pathway	IBA	J:265628
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:181884
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:102948
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:113403
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:113403
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:108509
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:108509
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:80206
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:104380
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:104380
Biological Process	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	IGI	J:158583
Biological Process	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	IGI	J:121232
Biological Process	GO:0021776	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	IGI	J:92067
Biological Process	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification	IGI	J:92067
Biological Process	GO:0021513	spinal cord dorsal/ventral patterning	IGI	J:92067
Biological Process	GO:0021513	spinal cord dorsal/ventral patterning	IGI	J:104803
Biological Process	GO:0021522	spinal cord motor neuron differentiation	IGI	J:188764
Biological Process	GO:0072089	stem cell proliferation	IMP	J:163175
Biological Process	GO:0072089	stem cell proliferation	IGI	J:163175
Biological Process	GO:0021544	subpallium development	IMP	J:165487
Biological Process	GO:0033077	T cell differentiation in thymus	IMP	J:117284
Biological Process	GO:0021537	telencephalon development	IMP	J:59923
Biological Process	GO:0021537	telencephalon development	IMP	J:142500
Biological Process	GO:0021537	telencephalon development	IMP	J:145009
Biological Process	GO:0070242	thymocyte apoptotic process	IMP	J:151855
Biological Process	GO:0043586	tongue development	IMP	J:139635
Biological Process	GO:0035295	tube development	IGI	J:49603
Biological Process	GO:0035295	tube development	IGI	J:49603
Biological Process	GO:0071625	vocalization behavior	IMP	J:241145

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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