GO Annotations Graph

• Symbol: Glul
• Name: glutamate-ammonia ligase
• ID: MGI:95739

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0045503	dynein light chain binding	ISO	J:155856
Molecular Function	GO:0016595	glutamate binding	ISO	J:155856
Molecular Function	GO:0004356	glutamate-ammonia ligase activity	ISO	J:155856
Molecular Function	GO:0004356	glutamate-ammonia ligase activity	ISO	J:164563
Molecular Function	GO:0004356	glutamate-ammonia ligase activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0016874	ligase activity	IEA	J:60000
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:155856
Molecular Function	GO:0030145	manganese ion binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:172995
Molecular Function	GO:0005515	protein binding	IPI	J:200967
Molecular Function	GO:0019706	protein-cysteine S-palmitoyltransferase activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0044297	cell body	IDA	J:197857
Cellular Component	GO:0042995	cell projection	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:85286
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0097386	glial cell projection	IDA	J:197857
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0043209	myelin sheath	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:155856
Biological Process	GO:0019676	ammonia assimilation cycle	ISO	J:155856
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0008283	cell population proliferation	ISO	J:164563
Biological Process	GO:0009267	cellular response to starvation	IEP	J:193325
Biological Process	GO:0006536	glutamate metabolic process	ISO	J:155856
Biological Process	GO:0006542	glutamine biosynthetic process	ISO	J:155856
Biological Process	GO:0006542	glutamine biosynthetic process	IBA	J:265628
Biological Process	GO:0006807	nitrogen compound metabolic process	IEA	J:72247
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	ISO	J:155856
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:155856
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	ISO	J:155856
Biological Process	GO:0018345	protein palmitoylation	ISO	J:164563
Biological Process	GO:0010594	regulation of endothelial cell migration	ISO	J:164563
Biological Process	GO:0010594	regulation of endothelial cell migration	IMP	J:265290
Biological Process	GO:1904749	regulation of protein localization to nucleolus	ISO	J:164563
Biological Process	GO:1903670	regulation of sprouting angiogenesis	IMP	J:265290
Biological Process	GO:1903670	regulation of sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0009749	response to glucose	IMP	J:128716
Biological Process	GO:0042254	ribosome biogenesis	ISO	J:164563