GO Annotations Graph

• Symbol: Glo1
• Name: glyoxalase 1
• ID: MGI:95742

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004462	lactoylglutathione lyase activity	ISO	J:164563
Molecular Function	GO:0004462	lactoylglutathione lyase activity	IDA	J:203406
Molecular Function	GO:0004462	lactoylglutathione lyase activity	ISO	J:155856
Molecular Function	GO:0004462	lactoylglutathione lyase activity	IDA	J:441
Molecular Function	GO:0004462	lactoylglutathione lyase activity	IDA	J:178902
Molecular Function	GO:0004462	lactoylglutathione lyase activity	IDA	J:5998
Molecular Function	GO:0004462	lactoylglutathione lyase activity	IDA	J:5879
Molecular Function	GO:0004462	lactoylglutathione lyase activity	IDA	J:6441
Molecular Function	GO:0004462	lactoylglutathione lyase activity	IDA	J:6704
Molecular Function	GO:0004462	lactoylglutathione lyase activity	IDA	J:6674
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IDA	J:203406
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0005975	carbohydrate metabolic process	ISO	J:155856
Biological Process	GO:0006749	glutathione metabolic process	ISO	J:155856
Biological Process	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IC	J:178902
Biological Process	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IC	J:6674
Biological Process	GO:0009438	methylglyoxal metabolic process	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:203406
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:126723