GO Annotations Graph

• Symbol: Gls
• Name: glutaminase
• ID: MGI:95752

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004359	glutaminase activity	IDA	J:184098
Molecular Function	GO:0004359	glutaminase activity	ISO	J:164563
Molecular Function	GO:0004359	glutaminase activity	IBA	J:265628
Molecular Function	GO:0004359	glutaminase activity	IMP	J:108409
Molecular Function	GO:0004359	glutaminase activity	IMP	J:182320
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	IPI	J:184098
Molecular Function	GO:0005515	protein binding	IPI	J:111737
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0045202	synapse	IMP	J:108409
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:108409
Biological Process	GO:0006537	glutamate biosynthetic process	IDA	J:184098
Biological Process	GO:0006537	glutamate biosynthetic process	ISO	J:164563
Biological Process	GO:0006537	glutamate biosynthetic process	IBA	J:265628
Biological Process	GO:0006543	glutamine catabolic process	IDA	J:184098
Biological Process	GO:0006543	glutamine catabolic process	ISO	J:164563
Biological Process	GO:0006543	glutamine catabolic process	IBA	J:265628
Biological Process	GO:0006543	glutamine catabolic process	IMP	J:108409
Biological Process	GO:0006541	glutamine metabolic process	IEA	J:72247
Biological Process	GO:0090461	intracellular glutamate homeostasis	ISO	J:164563
Biological Process	GO:0051289	protein homotetramerization	ISO	J:164563
Biological Process	GO:0051289	protein homotetramerization	IDA	J:184098
Biological Process	GO:0002087	regulation of respiratory gaseous exchange by nervous system process	IMP	J:108409
Biological Process	GO:0001967	suckling behavior	IMP	J:108409