GO Annotations Graph

• Symbol: Glud1
• Name: glutamate dehydrogenase 1
• ID: MGI:95753

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043531	ADP binding	ISO	J:164563
Molecular Function	GO:0043531	ADP binding	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0004352	glutamate dehydrogenase (NAD+) activity	ISO	J:164563
Molecular Function	GO:0004352	glutamate dehydrogenase (NAD+) activity	ISO	J:164563
Molecular Function	GO:0004352	glutamate dehydrogenase (NAD+) activity	IDA	J:166803
Molecular Function	GO:0004352	glutamate dehydrogenase (NAD+) activity	ISO	J:155856
Molecular Function	GO:0004352	glutamate dehydrogenase (NAD+) activity	IBA	J:265628
Molecular Function	GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	ISO	J:164563
Molecular Function	GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	ISO	J:164563
Molecular Function	GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	IDA	J:198927
Molecular Function	GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	IDA	J:129427
Molecular Function	GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	IDA	J:233904
Molecular Function	GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	IDA	J:73910
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0070728	leucine binding	ISO	J:164563
Molecular Function	GO:0070728	leucine binding	ISO	J:164563
Molecular Function	GO:0070403	NAD+ binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:166803
Molecular Function	GO:0005515	protein binding	IPI	J:129427
Molecular Function	GO:0005515	protein binding	IPI	J:200967
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005743	mitochondrial inner membrane	HDA	J:100953
Cellular Component	GO:0005759	mitochondrial matrix	IDA	J:129009
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	IDA	J:233904
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IDA	J:129427
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Biological Process	GO:0006520	amino acid metabolic process	IEA	J:72247
Biological Process	GO:0006538	glutamate catabolic process	IBA	J:265628
Biological Process	GO:0006541	glutamine metabolic process	IMP	J:198927
Biological Process	GO:0032024	positive regulation of insulin secretion	IGI	J:129427
Biological Process	GO:0010044	response to aluminum ion	ISO	J:155856
Biological Process	GO:0072350	tricarboxylic acid metabolic process	IMP	J:198927