GO Annotations Graph

• Symbol: Tle5
• Name: TLE family member 5, transcriptional modulator
• ID: MGI:95806

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:101190
Molecular Function	GO:0005515	protein binding	IPI	J:101190
Molecular Function	GO:0005515	protein binding	IPI	J:77680
Molecular Function	GO:0005515	protein binding	IPI	J:77680
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:77680
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-4649029
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:154112
Cellular Component	GO:0005634	nucleus	IDA	J:101190
Cellular Component	GO:0005634	nucleus	IDA	J:77680
Biological Process	GO:0031668	cellular response to extracellular stimulus	IDA	J:54434
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:77680
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0032091	negative regulation of protein binding	ISO	J:164563
Biological Process	GO:0060761	negative regulation of response to cytokine stimulus	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:2000210	positive regulation of anoikis	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0040008	regulation of growth	IMP	J:76397
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IGI	J:101190
Biological Process	GO:0070555	response to interleukin-1	ISO	J:164563
Biological Process	GO:0001501	skeletal system development	IMP	J:76397
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000