GO Annotations Graph

• Symbol: Gria1
• Name: glutamate receptor, ionotropic, AMPA1 (alpha 1)
• ID: MGI:95808

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008179	adenylate cyclase binding	ISO	J:155856
Molecular Function	GO:0004971	AMPA glutamate receptor activity	ISO	J:155856
Molecular Function	GO:0004971	AMPA glutamate receptor activity	ISO	J:164563
Molecular Function	GO:0004971	AMPA glutamate receptor activity	IBA	J:265628
Molecular Function	GO:0004971	AMPA glutamate receptor activity	IDA	J:260353
Molecular Function	GO:0001540	amyloid-beta binding	ISO	J:155856
Molecular Function	GO:0031698	beta-2 adrenergic receptor binding	ISO	J:155856
Molecular Function	GO:0001965	G-protein alpha-subunit binding	ISO	J:155856
Molecular Function	GO:0031681	G-protein beta-subunit binding	ISO	J:155856
Molecular Function	GO:0035254	glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0019865	immunoglobulin binding	ISO	J:155856
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	ISO	J:155856
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO	J:164563
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0031489	myosin V binding	ISO	J:155856
Molecular Function	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	IMP	J:238444
Molecular Function	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	IBA	J:265628
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:108736
Molecular Function	GO:0005515	protein binding	IPI	J:243400
Molecular Function	GO:0005515	protein binding	IPI	J:135974
Molecular Function	GO:0005515	protein binding	IPI	J:135974
Molecular Function	GO:0005515	protein binding	IPI	J:84278
Molecular Function	GO:0005515	protein binding	IPI	J:175149
Molecular Function	GO:0005515	protein binding	IPI	J:108736
Molecular Function	GO:0005515	protein binding	IPI	J:158601
Molecular Function	GO:0005515	protein binding	IPI	J:200294
Molecular Function	GO:0005515	protein binding	IPI	J:164372
Molecular Function	GO:0005515	protein binding	IPI	J:100200
Molecular Function	GO:0005515	protein binding	IPI	J:204158
Molecular Function	GO:0005515	protein binding	IPI	J:294276
Molecular Function	GO:0005515	protein binding	IPI	J:100200
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0051018	protein kinase A binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:155856
Molecular Function	GO:0038023	signaling receptor activity	IEA	J:72247
Molecular Function	GO:0031267	small GTPase binding	ISO	J:155856
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	ISO	J:155856
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IBA	J:265628
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IDA	J:260353
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IDA	J:76021
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IDA	J:76021
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IMP	J:76021
Cellular Component	GO:0032281	AMPA glutamate receptor complex	ISO	J:155856
Cellular Component	GO:0032281	AMPA glutamate receptor complex	IBA	J:265628
Cellular Component	GO:0032281	AMPA glutamate receptor complex	IDA	J:100200
Cellular Component	GO:0032281	AMPA glutamate receptor complex	IDA	J:188364
Cellular Component	GO:0032279	asymmetric synapse	ISO	J:155856
Cellular Component	GO:0044308	axonal spine	IDA	J:193911
Cellular Component	GO:0044297	cell body	IDA	J:205779
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	IDA	J:128028
Cellular Component	GO:0009986	cell surface	IMP	J:128028
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:221413
Cellular Component	GO:0009986	cell surface	IDA	J:205779
Cellular Component	GO:0009986	cell surface	IDA	J:197846
Cellular Component	GO:0009986	cell surface	IDA	J:256117
Cellular Component	GO:0005911	cell-cell junction	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IDA	J:167716
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IDA	J:260353
Cellular Component	GO:0030425	dendrite	IDA	J:205779
Cellular Component	GO:0030425	dendrite	IDA	J:193911
Cellular Component	GO:0032590	dendrite membrane	IDA	J:184110
Cellular Component	GO:0032590	dendrite membrane	ISO	J:155856
Cellular Component	GO:0032590	dendrite membrane	IMP	J:184110
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	IDA	J:167716
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	IBA	J:265628
Cellular Component	GO:0043197	dendritic spine	IDA	J:204158
Cellular Component	GO:0032591	dendritic spine membrane	ISO	J:164563
Cellular Component	GO:0032591	dendritic spine membrane	IDA	J:328024
Cellular Component	GO:0005769	early endosome	ISO	J:155856
Cellular Component	GO:0031901	early endosome membrane	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:111556
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:155856
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	IDA	J:221413
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:218184
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:105497
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:105497
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:76021
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:76021
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:76021
Cellular Component	GO:0008328	ionotropic glutamate receptor complex	IDA	J:150922
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:114917
Cellular Component	GO:0031594	neuromuscular junction	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IDA	J:173402
Cellular Component	GO:0044309	neuron spine	ISO	J:155856
Cellular Component	GO:0044309	neuron spine	IDA	J:108736
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	IDA	J:108736
Cellular Component	GO:0043025	neuronal cell body	IDA	J:221413
Cellular Component	GO:0043025	neuronal cell body	IDA	J:221413
Cellular Component	GO:0032809	neuronal cell body membrane	ISO	J:155856
Cellular Component	GO:0099544	perisynaptic space	IDA	J:260353
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:108736
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:210853
Cellular Component	GO:0005886	plasma membrane	IDA	J:294276
Cellular Component	GO:0098794	postsynapse	IDA	J:292854
Cellular Component	GO:0098794	postsynapse	IDA	J:237681
Cellular Component	GO:0014069	postsynaptic density	IDA	J:82443
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	IDA	J:96801
Cellular Component	GO:0014069	postsynaptic density	IDA	J:167716
Cellular Component	GO:0098839	postsynaptic density membrane	IC	J:105497
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Cellular Component	GO:0098839	postsynaptic density membrane	IBA	J:265628
Cellular Component	GO:0098839	postsynaptic density membrane	IDA	J:260353
Cellular Component	GO:0098839	postsynaptic density membrane	IDA	J:105497
Cellular Component	GO:0098839	postsynaptic density membrane	IDA	J:105497
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:150922
Cellular Component	GO:0098793	presynapse	IDA	J:292854
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0055037	recycling endosome	ISO	J:164563
Cellular Component	GO:0055038	recycling endosome membrane	ISO	J:155856
Cellular Component	GO:0036477	somatodendritic compartment	IDA	J:135974
Cellular Component	GO:0045202	synapse	IDA	J:314561
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:204158
Cellular Component	GO:0045202	synapse	ISO	J:96464
Cellular Component	GO:0097060	synaptic membrane	ISO	J:155856
Cellular Component	GO:0097060	synaptic membrane	IDA	J:201438
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:160616
Cellular Component	GO:0030672	synaptic vesicle membrane	IDA	J:260353
Biological Process	GO:0071242	cellular response to ammonium ion	IDA	J:210853
Biological Process	GO:0071242	cellular response to ammonium ion	IDA	J:210853
Biological Process	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	ISO	J:155856
Biological Process	GO:0007268	chemical synaptic transmission	IGI	J:151465
Biological Process	GO:0007616	long-term memory	IMP	J:82443
Biological Process	GO:0007616	long-term memory	ISO	J:155856
Biological Process	GO:0060292	long-term synaptic depression	IGI	J:204158
Biological Process	GO:0050804	modulation of chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0019228	neuronal action potential	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0045838	positive regulation of membrane potential	ISO	J:155856
Biological Process	GO:0050806	positive regulation of synaptic transmission	ISO	J:155856
Biological Process	GO:0031623	receptor internalization	ISO	J:155856
Biological Process	GO:0031623	receptor internalization	IMP	J:82443
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	IMP	J:76021
Biological Process	GO:0001919	regulation of receptor recycling	ISO	J:155856
Biological Process	GO:0048167	regulation of synaptic plasticity	ISO	J:155856
Biological Process	GO:0009636	response to toxic substance	ISO	J:155856
Biological Process	GO:0007416	synapse assembly	IMP	J:328024
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IBA	J:265628