Grik2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Grik2
glutamate receptor, ionotropic, kainate 2 (beta 2)
MGI:95815

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005234	extracellularly glutamate-gated ion channel activity	ISO	J:164563
Molecular Function	GO:0008066	glutamate receptor activity	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	IMP	J:114811
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	IDA	J:287030
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	ISO	J:155856
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	ISO	J:164563
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	IBA	J:265628
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	IMP	J:60965
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	IDA	J:696
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	IDA	J:109768
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	IMP	J:96594
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	IGI	J:97340
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	IMP	J:79143
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	IMP	J:97340
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	IDA	J:78109
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	IMP	J:79143
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	IMP	J:46932
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	IGI	J:696
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	IMP	J:52041
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	IDA	J:148310
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	IDA	J:148310
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	IEP	J:148310
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	IMP	J:148310
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	IDA	J:148310
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:114811
Molecular Function	GO:0005515	protein binding	IPI	J:174557
Molecular Function	GO:0005515	protein binding	IPI	J:174557
Molecular Function	GO:0005515	protein binding	IPI	J:85342
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:155856
Molecular Function	GO:0038023	signaling receptor activity	IEA	J:72247
Molecular Function	GO:0000149	SNARE binding	ISO	J:155856
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IBA	J:265628
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IDA	J:265622
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IDA	J:265622
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IMP	J:265622
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	EXP	J:265622
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IDA	J:265622
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IDA	J:46932
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IMP	J:46932
Molecular Function	GO:0031624	ubiquitin conjugating enzyme binding	ISO	J:155856
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0032839	dendrite cytoplasm	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:148310
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:148310
Cellular Component	GO:0098978	glutamatergic synapse	IEP	J:148310
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:148310
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:148310
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:238521
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:238521
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:238521
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:238521
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	EXP	J:265622
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IDA	J:265622
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IDA	J:265622
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IDA	J:265622
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IMP	J:265622
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IDA	J:46932
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IMP	J:46932
Cellular Component	GO:0008328	ionotropic glutamate receptor complex	ISO	J:155856
Cellular Component	GO:0008328	ionotropic glutamate receptor complex	IC	J:79143
Cellular Component	GO:0032983	kainate selective glutamate receptor complex	IBA	J:265628
Cellular Component	GO:0032983	kainate selective glutamate receptor complex	IPI	J:85342
Cellular Component	GO:0032983	kainate selective glutamate receptor complex	IPI	J:123244
Cellular Component	GO:0032983	kainate selective glutamate receptor complex	IPI	J:85342
Cellular Component	GO:0032983	kainate selective glutamate receptor complex	IPI	J:123244
Cellular Component	GO:0016020	membrane	IDA	J:85342
Cellular Component	GO:0097471	mossy fiber rosette	IDA	J:238521
Cellular Component	GO:0097471	mossy fiber rosette	IMP	J:238521
Cellular Component	GO:0097471	mossy fiber rosette	IDA	J:238521
Cellular Component	GO:0097471	mossy fiber rosette	IDA	J:238521
Cellular Component	GO:0043025	neuronal cell body	IDA	J:40245
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	IDA	J:174557
Cellular Component	GO:0098839	postsynaptic density membrane	IBA	J:265628
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:105519
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:238521
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:238521
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:238521
Cellular Component	GO:0045211	postsynaptic membrane	IMP	J:238521
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:238521
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:238521
Cellular Component	GO:0045211	postsynaptic membrane	IMP	J:238521
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:238521
Cellular Component	GO:0042734	presynaptic membrane	IBA	J:265628
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:105519
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:97340
Cellular Component	GO:0045202	synapse	TAS	J:114811
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:174557
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Biological Process	GO:0001662	behavioral fear response	IMP	J:98109
Biological Process	GO:0007268	chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0007268	chemical synaptic transmission	IGI	J:114338
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:114338
Biological Process	GO:0120169	detection of cold stimulus involved in thermoception	IMP	J:287030
Biological Process	GO:0060079	excitatory postsynaptic potential	IGI	J:97340
Biological Process	GO:0060079	excitatory postsynaptic potential	IMP	J:111580
Biological Process	GO:0060079	excitatory postsynaptic potential	IMP	J:105519
Biological Process	GO:0060080	inhibitory postsynaptic potential	IMP	J:52041
Biological Process	GO:0060080	inhibitory postsynaptic potential	IGI	J:60965
Biological Process	GO:0060080	inhibitory postsynaptic potential	IMP	J:79143
Biological Process	GO:0060080	inhibitory postsynaptic potential	IMP	J:60965
Biological Process	GO:0060080	inhibitory postsynaptic potential	IGI	J:66021
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IMP	J:104051
Biological Process	GO:0050804	modulation of chemical synaptic transmission	ISO	J:164563
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0098815	modulation of excitatory postsynaptic potential	ISO	J:155856
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:57544
Biological Process	GO:0051967	negative regulation of synaptic transmission, glutamatergic	ISO	J:155856
Biological Process	GO:0051967	negative regulation of synaptic transmission, glutamatergic	IGI	J:97340
Biological Process	GO:0051402	neuron apoptotic process	ISO	J:155856
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:57544
Biological Process	GO:0019228	neuronal action potential	IMP	J:107777
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0050806	positive regulation of synaptic transmission	ISO	J:164563
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IGI	J:97340
Biological Process	GO:0043113	receptor clustering	ISO	J:155856
Biological Process	GO:0046328	regulation of JNK cascade	ISO	J:155856
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	IMP	J:104051
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	IMP	J:98109
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	IMP	J:98109
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	IMP	J:89599
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	IMP	J:91763
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:60965
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:46392
Biological Process	GO:0042391	regulation of membrane potential	IGI	J:696
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:107790
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:79143
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:96594
Biological Process	GO:0042391	regulation of membrane potential	IDA	J:78109
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:104051
Biological Process	GO:0042391	regulation of membrane potential	IDA	J:696
Biological Process	GO:0048172	regulation of short-term neuronal synaptic plasticity	ISO	J:164563
Biological Process	GO:0048172	regulation of short-term neuronal synaptic plasticity	IMP	J:91763
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IBA	J:265628
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IMP	J:96594
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IMP	J:46932

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