Nr3c1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nr3c1
nuclear receptor subfamily 3, group C, member 1
MGI:95824

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:155856
Molecular Function	GO:0001046	core promoter sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:99071
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0034056	estrogen response element binding	IBA	J:265628
Molecular Function	GO:0031072	heat shock protein binding	ISO	J:155856
Molecular Function	GO:0042562	hormone binding	ISO	J:155856
Molecular Function	GO:0030544	Hsp70 protein binding	ISO	J:155856
Molecular Function	GO:0051879	Hsp90 protein binding	ISO	J:164563
Molecular Function	GO:0051879	Hsp90 protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	IPI	J:22585
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0140677	molecular function activator activity	ISO	J:164563
Molecular Function	GO:0004883	nuclear glucocorticoid receptor activity	IDA	J:41618
Molecular Function	GO:0004883	nuclear glucocorticoid receptor activity	IDA	J:91599
Molecular Function	GO:0004883	nuclear glucocorticoid receptor activity	IDA	J:41618
Molecular Function	GO:0004883	nuclear glucocorticoid receptor activity	IDA	J:19784
Molecular Function	GO:0004883	nuclear glucocorticoid receptor activity	IDA	J:41618
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:153344
Molecular Function	GO:0005515	protein binding	IPI	J:209571
Molecular Function	GO:0005515	protein binding	IPI	J:179376
Molecular Function	GO:0005515	protein binding	IPI	J:247279
Molecular Function	GO:0005515	protein binding	IPI	J:244975
Molecular Function	GO:0005515	protein binding	IPI	J:153344
Molecular Function	GO:0005515	protein binding	IPI	J:74637
Molecular Function	GO:0005515	protein binding	IPI	J:152609
Molecular Function	GO:0005515	protein binding	IPI	J:152609
Molecular Function	GO:0005515	protein binding	IPI	J:99071
Molecular Function	GO:0019901	protein kinase binding	IPI	J:162259
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:22585
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0005496	steroid binding	ISO	J:155856
Molecular Function	GO:0005496	steroid binding	ISO	J:164563
Molecular Function	GO:1990239	steroid hormone binding	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:155856
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IDA	J:247279
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:19784
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0005622	intracellular anatomical structure	IDA	J:41618
Cellular Component	GO:0016020	membrane	IDA	J:41618
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9009091
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9625700
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9769703
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IDA	J:19784
Cellular Component	GO:0005634	nucleus	IDA	J:99071
Cellular Component	GO:0005634	nucleus	IDA	J:71817
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0099092	postsynaptic density, intracellular component	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0030325	adrenal gland development	IMP	J:27441
Biological Process	GO:0048708	astrocyte differentiation	IMP	J:265067
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	ISO	J:164563
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	ISO	J:155856
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	ISO	J:164563
Biological Process	GO:0071383	cellular response to steroid hormone stimulus	ISO	J:164563
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	ISO	J:164563
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	ISO	J:155856
Biological Process	GO:0010467	gene expression	IMP	J:265067
Biological Process	GO:0043402	glucocorticoid mediated signaling pathway	IDA	J:41618
Biological Process	GO:0008211	glucocorticoid metabolic process	IMP	J:57509
Biological Process	GO:0042921	glucocorticoid receptor signaling pathway	IDA	J:41618
Biological Process	GO:0042921	glucocorticoid receptor signaling pathway	IDA	J:217874
Biological Process	GO:0042921	glucocorticoid receptor signaling pathway	IMP	J:27441
Biological Process	GO:0042921	glucocorticoid receptor signaling pathway	IMP	J:54615
Biological Process	GO:0042921	glucocorticoid receptor signaling pathway	IDA	J:91599
Biological Process	GO:0060603	mammary gland duct morphogenesis	IMP	J:125451
Biological Process	GO:0042711	maternal behavior	IGI	J:192857
Biological Process	GO:0042711	maternal behavior	IGI	J:192857
Biological Process	GO:0014004	microglia differentiation	IMP	J:265067
Biological Process	GO:0061744	motor behavior	IMP	J:265067
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0031914	negative regulation of synaptic plasticity	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0043116	negative regulation of vascular permeability	ISO	J:155856
Biological Process	GO:0150076	neuroinflammatory response	IMP	J:265067
Biological Process	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	ISO	J:155856
Biological Process	GO:0060999	positive regulation of dendritic spine development	ISO	J:155856
Biological Process	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway	ISO	J:155856
Biological Process	GO:0014049	positive regulation of glutamate secretion	ISO	J:155856
Biological Process	GO:1902895	positive regulation of miRNA transcription	IDA	J:217874
Biological Process	GO:1902895	positive regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IGI	J:61471
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0042127	regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:240279
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:54615
Biological Process	GO:0031946	regulation of glucocorticoid biosynthetic process	IMP	J:27441
Biological Process	GO:0006111	regulation of gluconeogenesis	IMP	J:27441
Biological Process	GO:0010906	regulation of glucose metabolic process	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0046685	response to arsenic-containing substance	ISO	J:155856
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IMP	J:265067
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	ISO	J:155856

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24