GO Annotations Graph

• Symbol: Pdia3
• Name: protein disulfide isomerase associated 3
• ID: MGI:95834

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016853	isomerase activity	IEA	J:60000
Molecular Function	GO:0042288	MHC class I protein binding	ISO	J:155856
Molecular Function	GO:0008233	peptidase activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:167004
Molecular Function	GO:0005515	protein binding	IPI	J:289677
Molecular Function	GO:0005515	protein binding	IPI	J:198051
Molecular Function	GO:0005515	protein binding	IPI	J:198051
Molecular Function	GO:0003756	protein disulfide isomerase activity	IBA	J:265628
Molecular Function	GO:0019153	protein-disulfide reductase (glutathione) activity	ISO	J:155856
Molecular Function	GO:0015035	protein-disulfide reductase activity	ISO	J:164563
Cellular Component	GO:0001669	acrosomal vesicle	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0009986	cell surface	IDA	J:182119
Cellular Component	GO:0009986	cell surface	ISO	J:73065
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:46305
Cellular Component	GO:0005788	endoplasmic reticulum lumen	TAS	Reactome:R-MMU-983160
Cellular Component	GO:0005576	extracellular region	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0042824	MHC class I peptide loading complex	ISO	J:155856
Cellular Component	GO:0042824	MHC class I peptide loading complex	ISO	J:164563
Cellular Component	GO:0005758	mitochondrial intermembrane space	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005790	smooth endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0042825	TAP complex	ISO	J:155856
Cellular Component	GO:0061779	Tapasin-ERp57 complex	ISO	J:164563
Biological Process	GO:0098761	cellular response to interleukin-7	IDA	J:260356
Biological Process	GO:0071305	cellular response to vitamin D	ISO	J:155856
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	IMP	J:98374
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	IMP	J:98374
Biological Process	GO:0002502	peptide antigen assembly with MHC class I protein complex	ISO	J:164563
Biological Process	GO:0070527	platelet aggregation	IMP	J:244748
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	IMP	J:98374
Biological Process	GO:1903334	positive regulation of protein folding	ISO	J:155856
Biological Process	GO:0006457	protein folding	IBA	J:265628
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IBA	J:265628