GO Annotations Graph

• Symbol: Gstp1
• Name: glutathione S-transferase, pi 1
• ID: MGI:95865

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035731	dinitrosyl-iron complex binding	ISO	J:164563
Molecular Function	GO:0005504	fatty acid binding	ISO	J:164563
Molecular Function	GO:0004602	glutathione peroxidase activity	ISO	J:164563
Molecular Function	GO:0004364	glutathione transferase activity	ISO	J:164563
Molecular Function	GO:0004364	glutathione transferase activity	IBA	J:265628
Molecular Function	GO:0004364	glutathione transferase activity	IDA	J:21716
Molecular Function	GO:0008432	JUN kinase binding	IPI	J:172900
Molecular Function	GO:0019207	kinase regulator activity	IMP	J:124412
Molecular Function	GO:0097159	organic cyclic compound binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0035730	S-nitrosoglutathione binding	ISO	J:164563
Molecular Function	GO:0015643	toxic substance binding	ISO	J:155856
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	IDA	J:172900
Cellular Component	GO:0097057	TRAF2-GSTP1 complex	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IDA	J:172998
Biological Process	GO:0035726	common myeloid progenitor cell proliferation	IMP	J:172896
Biological Process	GO:1901687	glutathione derivative biosynthetic process	ISO	J:164563
Biological Process	GO:0006749	glutathione metabolic process	ISO	J:164563
Biological Process	GO:0006749	glutathione metabolic process	IBA	J:265628
Biological Process	GO:0006749	glutathione metabolic process	IDA	J:21716
Biological Process	GO:0051122	hepoxilin biosynthetic process	ISO	J:164563
Biological Process	GO:0043651	linoleic acid metabolic process	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0002674	negative regulation of acute inflammatory response	NAS	J:172963
Biological Process	GO:0043066	negative regulation of apoptotic process	TAS	J:172963
Biological Process	GO:0009890	negative regulation of biosynthetic process	ISO	J:164563
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	IDA	J:172998
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	IMP	J:172896
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	IDA	J:172998
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	IDA	J:172963
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	ISO	J:164563
Biological Process	GO:0043508	negative regulation of JUN kinase activity	IDA	J:172998
Biological Process	GO:0043508	negative regulation of JUN kinase activity	IDA	J:172907
Biological Process	GO:0043508	negative regulation of JUN kinase activity	ISO	J:164563
Biological Process	GO:0043508	negative regulation of JUN kinase activity	IMP	J:124412
Biological Process	GO:0070664	negative regulation of leukocyte proliferation	IMP	J:172896
Biological Process	GO:0043407	negative regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0071638	negative regulation of monocyte chemotactic protein-1 production	ISO	J:164563
Biological Process	GO:0071638	negative regulation of monocyte chemotactic protein-1 production	IDA	J:172963
Biological Process	GO:2000429	negative regulation of neutrophil aggregation	NAS	J:172963
Biological Process	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	ISO	J:164563
Biological Process	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	IDA	J:172998
Biological Process	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	IDA	J:172963
Biological Process	GO:2000469	negative regulation of peroxidase activity	IDA	J:172963
Biological Process	GO:0006469	negative regulation of protein kinase activity	ISO	J:155856
Biological Process	GO:0006469	negative regulation of protein kinase activity	ISO	J:164563
Biological Process	GO:0071672	negative regulation of smooth muscle cell chemotaxis	ISO	J:155856
Biological Process	GO:0032873	negative regulation of stress-activated MAPK cascade	IDA	J:172998
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	IDA	J:172998
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	IDA	J:172963
Biological Process	GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0032930	positive regulation of superoxide anion generation	IMP	J:172896
Biological Process	GO:0006693	prostaglandin metabolic process	ISO	J:164563
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	IDA	J:172907
Biological Process	GO:0032872	regulation of stress-activated MAPK cascade	IDA	J:172907
Biological Process	GO:0000302	response to reactive oxygen species	IDA	J:172907
Biological Process	GO:0006805	xenobiotic metabolic process	ISO	J:164563