GO Annotations Graph

• Symbol: Selenos
• Name: selenoprotein S
• ID: MGI:95994

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016209	antioxidant activity	ISO	J:164563
Molecular Function	GO:0051117	ATPase binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:215393
Molecular Function	GO:0005515	protein binding	IPI	J:159130
Molecular Function	GO:1990381	ubiquitin-specific protease binding	ISO	J:164563
Cellular Component	GO:0005881	cytoplasmic microtubule	ISO	J:164563
Cellular Component	GO:0036513	Derlin-1 retrotranslocation complex	ISO	J:164563
Cellular Component	GO:0036513	Derlin-1 retrotranslocation complex	IBA	J:265628
Cellular Component	GO:0036502	Derlin-1-VIMP complex	ISO	J:164563
Cellular Component	GO:0036502	Derlin-1-VIMP complex	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0034362	low-density lipoprotein particle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0034361	very-low-density lipoprotein particle	ISO	J:164563
Biological Process	GO:0045454	cell redox homeostasis	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0034599	cellular response to oxidative stress	ISO	J:164563
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	ISO	J:164563
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	IBA	J:265628
Biological Process	GO:0006983	ER overload response	ISO	J:164563
Biological Process	GO:0006886	intracellular protein transport	IEA	J:72247
Biological Process	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	ISO	J:164563
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0050728	negative regulation of inflammatory response	IC	J:131465
Biological Process	GO:0032715	negative regulation of interleukin-6 production	IMP	J:131465
Biological Process	GO:2000110	negative regulation of macrophage apoptotic process	ISO	J:164563
Biological Process	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	ISO	J:164563
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	IMP	J:131465
Biological Process	GO:0080164	regulation of nitric oxide metabolic process	ISO	J:164563
Biological Process	GO:0051775	response to redox state	ISO	J:164563
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	ISO	J:164563
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	IBA	J:265628
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	ISO	J:164563
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	IBA	J:265628