GO Annotations Graph

• Symbol: Hbb-b1
• Name: hemoglobin, beta adult major chain
• ID: MGI:96021

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031720	haptoglobin binding	ISO	J:164563
Molecular Function	GO:0031720	haptoglobin binding	IBA	J:265628
Molecular Function	GO:0020037	heme binding	IBA	J:265628
Molecular Function	GO:0031721	hemoglobin alpha binding	ISO	J:155856
Molecular Function	GO:0031721	hemoglobin alpha binding	IBA	J:265628
Molecular Function	GO:0031722	hemoglobin beta binding	ISO	J:155856
Molecular Function	GO:0030492	hemoglobin binding	ISO	J:164563
Molecular Function	GO:0043177	organic acid binding	IBA	J:265628
Molecular Function	GO:0019825	oxygen binding	ISO	J:155856
Molecular Function	GO:0019825	oxygen binding	ISO	J:164563
Molecular Function	GO:0019825	oxygen binding	IBA	J:265628
Molecular Function	GO:0005344	oxygen carrier activity	IBA	J:265628
Molecular Function	GO:0005344	oxygen carrier activity	IMP	J:78271
Molecular Function	GO:0004601	peroxidase activity	ISO	J:164563
Molecular Function	GO:0004601	peroxidase activity	IBA	J:265628
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0031838	haptoglobin-hemoglobin complex	ISO	J:164563
Cellular Component	GO:0031838	haptoglobin-hemoglobin complex	IBA	J:265628
Cellular Component	GO:0005833	hemoglobin complex	ISO	J:164563
Cellular Component	GO:0005833	hemoglobin complex	IPI	J:322685
Cellular Component	GO:0005833	hemoglobin complex	ISO	J:164563
Cellular Component	GO:0005833	hemoglobin complex	ISO	J:155856
Cellular Component	GO:0005833	hemoglobin complex	IBA	J:265628
Cellular Component	GO:0005833	hemoglobin complex	IMP	J:30155
Cellular Component	GO:0005833	hemoglobin complex	IDA	J:78271
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Biological Process	GO:0015670	carbon dioxide transport	NAS	J:322684
Biological Process	GO:0048821	erythrocyte development	IGI	J:30155
Biological Process	GO:0030097	hemopoiesis	IMP	J:78271
Biological Process	GO:0042744	hydrogen peroxide catabolic process	IBA	J:265628
Biological Process	GO:0015671	oxygen transport	IMP	J:78271
Biological Process	GO:0010999	regulation of eIF2 alpha phosphorylation by heme	IMP	J:99200