GO Annotations Graph

• Symbol: Hc
• Name: hemolytic complement
• ID: MGI:96031

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004866	endopeptidase inhibitor activity	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IEA	J:72247
Cellular Component	GO:0005579	membrane attack complex	ISO	J:164563
Cellular Component	GO:0005579	membrane attack complex	ISO	J:164563
Biological Process	GO:0006956	complement activation	ISO	J:164563
Biological Process	GO:0006957	complement activation, alternative pathway	IEA	J:60000
Biological Process	GO:0006958	complement activation, classical pathway	IEA	J:60000
Biological Process	GO:0019835	cytolysis	IEA	J:60000
Biological Process	GO:0032835	glomerulus development	IGI	J:111031
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0001701	in utero embryonic development	IGI	J:145047
Biological Process	GO:0006954	inflammatory response	IEA	J:60000
Biological Process	GO:0090594	inflammatory response to wounding	IGI	J:185883
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0001822	kidney development	IGI	J:111031
Biological Process	GO:0010760	negative regulation of macrophage chemotaxis	ISO	J:164563
Biological Process	GO:0001780	neutrophil homeostasis	IGI	J:111031
Biological Process	GO:0045766	positive regulation of angiogenesis	IMP	J:106063
Biological Process	GO:0032722	positive regulation of chemokine production	ISO	J:164563
Biological Process	GO:0050778	positive regulation of immune response	NAS	J:320051
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	ISO	J:164563