Hhex GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Hhex
hematopoietically expressed homeobox
MGI:96086

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:110528
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0008301	DNA binding, bending	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:156073
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA	J:72247
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:110528
Molecular Function	GO:0008190	eukaryotic initiation factor 4E binding	ISO	J:164563
Molecular Function	GO:0071837	HMG box domain binding	IPI	J:175179
Molecular Function	GO:0005515	protein binding	IPI	J:161671
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:110528
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:114930
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:74064
Cellular Component	GO:0005634	nucleus	IDA	J:114930
Cellular Component	GO:0032993	protein-DNA complex	ISO	J:164563
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:87725
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:133012
Biological Process	GO:0030183	B cell differentiation	IMP	J:81415
Biological Process	GO:0030154	cell differentiation	ISO	J:155856
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0061009	common bile duct development	IMP	J:124126
Biological Process	GO:0071103	DNA conformation change	ISO	J:164563
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:93580
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:93580
Biological Process	GO:0048568	embryonic organ development	IMP	J:119866
Biological Process	GO:0007492	endoderm development	IMP	J:119866
Biological Process	GO:0030900	forebrain development	IMP	J:62027
Biological Process	GO:0030900	forebrain development	IMP	J:74125
Biological Process	GO:0030900	forebrain development	IMP	J:93580
Biological Process	GO:0048853	forebrain morphogenesis	IMP	J:171680
Biological Process	GO:0061010	gallbladder development	IMP	J:124126
Biological Process	GO:0030097	hemopoiesis	IMP	J:107459
Biological Process	GO:0030097	hemopoiesis	IMP	J:85841
Biological Process	GO:0061011	hepatic duct development	IMP	J:124126
Biological Process	GO:0061017	hepatoblast differentiation	IMP	J:124126
Biological Process	GO:0070365	hepatocyte differentiation	IMP	J:65105
Biological Process	GO:0001701	in utero embryonic development	IMP	J:171680
Biological Process	GO:0022027	interkinetic nuclear migration	IMP	J:119866
Biological Process	GO:0001889	liver development	IMP	J:93580
Biological Process	GO:0001889	liver development	IMP	J:62027
Biological Process	GO:0001889	liver development	IMP	J:119866
Biological Process	GO:0001889	liver development	IMP	J:65105
Biological Process	GO:0002009	morphogenesis of an epithelium	IMP	J:124126
Biological Process	GO:0006406	mRNA export from nucleus	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0035264	multicellular organism growth	IMP	J:171680
Biological Process	GO:0002573	myeloid leukocyte differentiation	IMP	J:65105
Biological Process	GO:0016525	negative regulation of angiogenesis	ISO	J:155856
Biological Process	GO:0016525	negative regulation of angiogenesis	IDA	J:133016
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:133018
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:133016
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:133018
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:110528
Biological Process	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	ISO	J:155856
Biological Process	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	IDA	J:133016
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:218171
Biological Process	GO:0031016	pancreas development	IMP	J:119866
Biological Process	GO:0016973	poly(A)+ mRNA export from nucleus	ISO	J:164563
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	IMP	J:133012
Biological Process	GO:0060431	primary lung bud formation	IMP	J:119866
Biological Process	GO:0090009	primitive streak formation	IMP	J:171680
Biological Process	GO:0090009	primitive streak formation	IGI	J:171680
Biological Process	GO:0034504	protein localization to nucleus	ISO	J:164563
Biological Process	GO:0042127	regulation of cell population proliferation	IMP	J:87725
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0070663	regulation of leukocyte proliferation	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:171680
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:171680
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:171680
Biological Process	GO:0007165	signal transduction	IMP	J:171680
Biological Process	GO:0030878	thyroid gland development	IMP	J:95017
Biological Process	GO:0030878	thyroid gland development	IMP	J:62027
Biological Process	GO:0048729	tissue morphogenesis	IMP	J:171680
Biological Process	GO:0001570	vasculogenesis	IMP	J:107459
Biological Process	GO:0001570	vasculogenesis	IMP	J:85841
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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