GO Annotations Graph

• Symbol: Hoxb4
• Name: homeobox B4
• ID: MGI:96185

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:18886
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619426
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0009952	anterior/posterior pattern specification	IBA	J:265628
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:62577
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:62577
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:37682
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:62577
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:62577
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:37682
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:62577
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:62577
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:27467
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:62577
Biological Process	GO:0048539	bone marrow development	IMP	J:90976
Biological Process	GO:0060216	definitive hemopoiesis	IGI	J:126371
Biological Process	GO:0060216	definitive hemopoiesis	IGI	J:126371
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IBA	J:265628
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IGI	J:62577
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IGI	J:62577
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IGI	J:62577
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IGI	J:27467
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IGI	J:62577
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IGI	J:62577
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IGI	J:62577
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IGI	J:62577
Biological Process	GO:0060218	hematopoietic stem cell differentiation	ISO	J:164563
Biological Process	GO:0071425	hematopoietic stem cell proliferation	IMP	J:90976
Biological Process	GO:0071425	hematopoietic stem cell proliferation	IMP	J:90976
Biological Process	GO:0030097	hemopoiesis	IMP	J:90976
Biological Process	GO:0030097	hemopoiesis	IMP	J:90976
Biological Process	GO:0002011	morphogenesis of an epithelial sheet	IGI	J:71389
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:33051
Biological Process	GO:2000738	positive regulation of stem cell differentiation	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0048705	skeletal system morphogenesis	IMP	J:37682
Biological Process	GO:0048705	skeletal system morphogenesis	IGI	J:37682
Biological Process	GO:0048103	somatic stem cell division	IDA	J:83550
Biological Process	GO:0048536	spleen development	IMP	J:90976