GO Annotations Graph

• Symbol: Hp
• Name: haptoglobin
• ID: MGI:96211

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016209	antioxidant activity	IEA	J:60000
Molecular Function	GO:0030492	hemoglobin binding	ISO	J:155856
Molecular Function	GO:0030492	hemoglobin binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0004252	serine-type endopeptidase activity	IBA	J:265628
Cellular Component	GO:0072562	blood microparticle	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	ISO	J:73065
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0031838	haptoglobin-hemoglobin complex	ISO	J:164563
Cellular Component	GO:0034366	spherical high-density lipoprotein particle	ISO	J:164563
Biological Process	GO:0002526	acute inflammatory response	IBA	J:265628
Biological Process	GO:0006953	acute-phase response	IEA	J:60000
Biological Process	GO:0042742	defense response to bacterium	IEA	J:60000
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0001889	liver development	ISO	J:155856
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:216917
Biological Process	GO:0010942	positive regulation of cell death	IBA	J:265628
Biological Process	GO:0006508	proteolysis	IEA	J:72247
Biological Process	GO:0009617	response to bacterium	IEP	J:190322