GO Annotations Graph

• Symbol: Lipc
• Name: lipase, hepatic
• ID: MGI:96216

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity	IEA	J:72245
Molecular Function	GO:0008126	acetylesterase activity	ISO	J:155856
Molecular Function	GO:0047372	acylglycerol lipase activity	ISO	J:155856
Molecular Function	GO:0016746	acyltransferase activity	ISO	J:155856
Molecular Function	GO:0034185	apolipoprotein binding	ISO	J:155856
Molecular Function	GO:0034185	apolipoprotein binding	IBA	J:265628
Molecular Function	GO:0052689	carboxylic ester hydrolase activity	IEA	J:72247
Molecular Function	GO:0035478	chylomicron binding	ISO	J:155856
Molecular Function	GO:0043395	heparan sulfate proteoglycan binding	ISO	J:155856
Molecular Function	GO:0008201	heparin binding	ISO	J:155856
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0016298	lipase activity	IBA	J:265628
Molecular Function	GO:0016298	lipase activity	IDA	J:100492
Molecular Function	GO:0016298	lipase activity	IDA	J:85532
Molecular Function	GO:0008289	lipid binding	ISO	J:155856
Molecular Function	GO:0030169	low-density lipoprotein particle binding	ISO	J:155856
Molecular Function	GO:0004622	lysophospholipase activity	ISO	J:155856
Molecular Function	GO:0102545	phosphatidyl phospholipase B activity	IEA	J:72245
Molecular Function	GO:0052739	phosphatidylserine 1-acylhydrolase activity	IEA	J:72245
Molecular Function	GO:0008970	phospholipase A1 activity	ISO	J:155856
Molecular Function	GO:0008970	phospholipase A1 activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:156963
Molecular Function	GO:0004806	triglyceride lipase activity	ISO	J:164563
Molecular Function	GO:0004806	triglyceride lipase activity	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005769	early endosome	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:100492
Cellular Component	GO:0034364	high-density lipoprotein particle	IEA	J:60000
Cellular Component	GO:0005770	late endosome	ISO	J:155856
Cellular Component	GO:0005902	microvillus	ISO	J:155856
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	IGI	J:55745
Biological Process	GO:0008203	cholesterol metabolic process	IGI	J:55745
Biological Process	GO:0030301	cholesterol transport	IMP	J:35143
Biological Process	GO:0034382	chylomicron remnant clearance	ISO	J:155856
Biological Process	GO:0034371	chylomicron remodeling	ISO	J:155856
Biological Process	GO:0006633	fatty acid biosynthetic process	ISO	J:164563
Biological Process	GO:0006631	fatty acid metabolic process	ISO	J:155856
Biological Process	GO:0046475	glycerophospholipid catabolic process	ISO	J:155856
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	ISO	J:155856
Biological Process	GO:0034375	high-density lipoprotein particle remodeling	ISO	J:164563
Biological Process	GO:0034375	high-density lipoprotein particle remodeling	ISO	J:155856
Biological Process	GO:0016042	lipid catabolic process	IBA	J:265628
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:72247
Biological Process	GO:0034383	low-density lipoprotein particle clearance	ISO	J:155856
Biological Process	GO:0034374	low-density lipoprotein particle remodeling	ISO	J:164563
Biological Process	GO:0034374	low-density lipoprotein particle remodeling	ISO	J:155856
Biological Process	GO:0046461	neutral lipid catabolic process	ISO	J:155856
Biological Process	GO:0046473	phosphatidic acid metabolic process	ISO	J:155856
Biological Process	GO:0046470	phosphatidylcholine metabolic process	ISO	J:155856
Biological Process	GO:0046337	phosphatidylethanolamine metabolic process	ISO	J:155856
Biological Process	GO:0006658	phosphatidylserine metabolic process	ISO	J:155856
Biological Process	GO:0097006	regulation of plasma lipoprotein particle levels	ISO	J:155856
Biological Process	GO:0019433	triglyceride catabolic process	ISO	J:164563
Biological Process	GO:0070328	triglyceride homeostasis	ISO	J:164563
Biological Process	GO:0006641	triglyceride metabolic process	ISO	J:155856
Biological Process	GO:0034372	very-low-density lipoprotein particle remodeling	ISO	J:155856
Biological Process	GO:0034372	very-low-density lipoprotein particle remodeling	ISO	J:164563