GO Annotations Graph

• Symbol: Hprt1
• Name: hypoxanthine phosphoribosyltransferase 1
• ID: MGI:96217

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016757	glycosyltransferase activity	IEA	J:60000
Molecular Function	GO:0052657	guanine phosphoribosyltransferase activity	ISO	J:164563
Molecular Function	GO:0052657	guanine phosphoribosyltransferase activity	IMP	J:308550
Molecular Function	GO:0052657	guanine phosphoribosyltransferase activity	ISO	J:306609
Molecular Function	GO:0052657	guanine phosphoribosyltransferase activity	IMP	J:53129
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	ISO	J:164563
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	ISO	J:155856
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IBA	J:265628
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	J:53129
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	J:38586
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	J:53129
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	J:38586
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	J:308550
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:297526
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	MGI:MGI:51991
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	J:53129
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:5946
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:8903
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	J:15485
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	MGI:MGI:51991
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:5872
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	MGI:MGI:51991
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:38586
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:5618
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:6291
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:9627
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:6384
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:85443
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	MGI:MGI:51991
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	J:15483
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:11842
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:7062
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	J:35822
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:9720
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:5817
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	MGI:MGI:51991
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IMP	MGI:MGI:51991
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:20092
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	J:6224
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:103507
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:164563
Molecular Function	GO:0000287	magnesium ion binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:17722
Cellular Component	GO:0005737	cytoplasm	IDA	J:17722
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005829	cytosol	IDA	J:306118
Biological Process	GO:0046083	adenine metabolic process	IGI	J:35822
Biological Process	GO:0044209	AMP salvage	IDA	J:53129
Biological Process	GO:0044209	AMP salvage	IDA	J:297526
Biological Process	GO:0044209	AMP salvage	IDA	J:308794
Biological Process	GO:0021954	central nervous system neuron development	IMP	J:51651
Biological Process	GO:0021895	cerebral cortex neuron differentiation	IMP	J:107966
Biological Process	GO:0048813	dendrite morphogenesis	IMP	J:107966
Biological Process	GO:0042417	dopamine metabolic process	IMP	J:51651
Biological Process	GO:0042417	dopamine metabolic process	IMP	J:17905
Biological Process	GO:0042417	dopamine metabolic process	IMP	J:17798
Biological Process	GO:0071542	dopaminergic neuron differentiation	IMP	J:107966
Biological Process	GO:0046038	GMP catabolic process	ISO	J:164563
Biological Process	GO:0032263	GMP salvage	IBA	J:265628
Biological Process	GO:0032263	GMP salvage	IMP	J:308550
Biological Process	GO:0032263	GMP salvage	IMP	J:53129
Biological Process	GO:0032263	GMP salvage	ISO	J:306609
Biological Process	GO:0032263	GMP salvage	IMP	J:308550
Biological Process	GO:0032263	GMP salvage	IMP	J:53129
Biological Process	GO:0007625	grooming behavior	IGI	J:4123
Biological Process	GO:0006178	guanine salvage	ISO	J:164563
Biological Process	GO:0006178	guanine salvage	IBA	J:265628
Biological Process	GO:0046100	hypoxanthine metabolic process	ISO	J:164563
Biological Process	GO:0046100	hypoxanthine metabolic process	ISO	J:155856
Biological Process	GO:0046100	hypoxanthine metabolic process	IBA	J:265628
Biological Process	GO:0046100	hypoxanthine metabolic process	IMP	J:53129
Biological Process	GO:0046100	hypoxanthine metabolic process	IC	J:5817
Biological Process	GO:0046100	hypoxanthine metabolic process	IMP	J:15485
Biological Process	GO:0043103	hypoxanthine salvage	ISO	J:164563
Biological Process	GO:0046040	IMP metabolic process	ISO	J:164563
Biological Process	GO:0032264	IMP salvage	IBA	J:265628
Biological Process	GO:0032264	IMP salvage	IMP	J:38586
Biological Process	GO:0032264	IMP salvage	IMP	J:53129
Biological Process	GO:0007626	locomotory behavior	IMP	J:84451
Biological Process	GO:0046651	lymphocyte proliferation	IMP	J:85443
Biological Process	GO:0045964	positive regulation of dopamine metabolic process	ISO	J:164563
Biological Process	GO:0051289	protein homotetramerization	ISO	J:164563
Biological Process	GO:0006164	purine nucleotide biosynthetic process	ISO	J:164563
Biological Process	GO:0006166	purine ribonucleoside salvage	ISO	J:164563
Biological Process	GO:0006166	purine ribonucleoside salvage	IMP	J:4123
Biological Process	GO:0006166	purine ribonucleoside salvage	IMP	J:85443
Biological Process	GO:0006166	purine ribonucleoside salvage	IMP	J:53129
Biological Process	GO:0006166	purine ribonucleoside salvage	IMP	J:11842
Biological Process	GO:0006166	purine ribonucleoside salvage	IGI	J:4123
Biological Process	GO:0001975	response to amphetamine	IMP	J:17905
Biological Process	GO:0001975	response to amphetamine	IMP	J:1847
Biological Process	GO:0021756	striatum development	IMP	J:51651
Biological Process	GO:0001913	T cell mediated cytotoxicity	IMP	J:85443