Hras GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Hras
Harvey rat sarcoma virus oncogene
MGI:96224

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003925	G protein activity	IEA	J:72245
Molecular Function	GO:0019003	GDP binding	ISO	J:164563
Molecular Function	GO:0019003	GDP binding	IBA	J:265628
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	IBA	J:265628
Molecular Function	GO:0005525	GTP binding	IDA	J:145651
Molecular Function	GO:0003924	GTPase activity	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:46202
Molecular Function	GO:0005515	protein binding	IPI	J:194542
Molecular Function	GO:0005515	protein binding	IPI	J:64313
Molecular Function	GO:0005515	protein binding	IPI	J:137819
Molecular Function	GO:0005515	protein binding	IPI	J:91790
Molecular Function	GO:0005515	protein binding	IPI	J:36812
Molecular Function	GO:0005515	protein binding	IPI	J:117391
Molecular Function	GO:0005515	protein binding	IPI	J:145651
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	IDA	J:104992
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	IDA	J:104992
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0043495	protein-membrane adaptor activity	IDA	J:104992
Molecular Function	GO:0043495	protein-membrane adaptor activity	IDA	J:104992
Molecular Function	GO:0043495	protein-membrane adaptor activity	IDA	J:104992
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:1905360	GTPase complex	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9029152
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-1250468
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-1250472
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:124964
Biological Process	GO:0060612	adipose tissue development	IMP	J:298397
Biological Process	GO:0006915	apoptotic process	ISO	J:155856
Biological Process	GO:0071480	cellular response to gamma radiation	ISO	J:164563
Biological Process	GO:0090398	cellular senescence	ISO	J:164563
Biological Process	GO:0090398	cellular senescence	IBA	J:265628
Biological Process	GO:0090398	cellular senescence	IDA	J:95113
Biological Process	GO:0090398	cellular senescence	IDA	J:84791
Biological Process	GO:0042832	defense response to protozoan	IMP	J:173261
Biological Process	GO:0006897	endocytosis	IDA	J:81687
Biological Process	GO:0048144	fibroblast proliferation	IDA	J:106576
Biological Process	GO:0008286	insulin receptor signaling pathway	IDA	J:326913
Biological Process	GO:0008286	insulin receptor signaling pathway	IDA	J:326913
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	ISO	J:327224
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	IMP	J:117391
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	IGI	J:117391
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0034260	negative regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IDA	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:63722
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:63722
Biological Process	GO:0051402	neuron apoptotic process	IDA	J:63722
Biological Process	GO:0090402	oncogene-induced cell senescence	IDA	J:72780
Biological Process	GO:2000251	positive regulation of actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	IPI	J:88364
Biological Process	GO:0045740	positive regulation of DNA replication	ISO	J:155856
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	IDA	J:106576
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:170688
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0046330	positive regulation of JNK cascade	ISO	J:164563
Biological Process	GO:0043406	positive regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:2000630	positive regulation of miRNA metabolic process	ISO	J:164563
Biological Process	GO:0010863	positive regulation of phospholipase C activity	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	ISO	J:164563
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	ISO	J:145554
Biological Process	GO:1900029	positive regulation of ruffle assembly	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0032729	positive regulation of type II interferon production	IMP	J:173261
Biological Process	GO:0090303	positive regulation of wound healing	ISO	J:164563
Biological Process	GO:0007265	Ras protein signal transduction	IGI	J:76551
Biological Process	GO:0007265	Ras protein signal transduction	ISO	J:164563
Biological Process	GO:0007265	Ras protein signal transduction	ISO	J:155856
Biological Process	GO:0007265	Ras protein signal transduction	IBA	J:265628
Biological Process	GO:0007265	Ras protein signal transduction	TAS	J:62962
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0042127	regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	IMP	J:98903
Biological Process	GO:0043405	regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0098696	regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0007264	small GTPase mediated signal transduction	IDA	J:88364
Biological Process	GO:0050852	T cell receptor signaling pathway	IMP	J:173261
Biological Process	GO:0042088	T-helper 1 type immune response	IMP	J:173261

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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