GO Annotations Graph

• Symbol: Hspa2
• Name: heat shock protein 2
• ID: MGI:96243

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016887	ATP hydrolysis activity	IBA	J:265628
Molecular Function	GO:0140662	ATP-dependent protein folding chaperone	IEA	J:72247
Molecular Function	GO:0097718	disordered domain specific binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0051861	glycolipid binding	IDA	J:43533
Molecular Function	GO:0031072	heat shock protein binding	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:139505
Molecular Function	GO:0005515	protein binding	IPI	J:228105
Molecular Function	GO:0005515	protein binding	IPI	J:161124
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0005515	protein binding	IPI	J:123481
Molecular Function	GO:0005515	protein binding	IPI	J:77458
Molecular Function	GO:0005515	protein binding	IPI	J:193087
Molecular Function	GO:0044183	protein folding chaperone	IBA	J:265628
Molecular Function	GO:0051087	protein-folding chaperone binding	ISO	J:155856
Molecular Function	GO:0048156	tau protein binding	ISO	J:155856
Molecular Function	GO:0051082	unfolded protein binding	ISO	J:164563
Cellular Component	GO:0036128	CatSper complex	IDA	J:182472
Cellular Component	GO:0009986	cell surface	IDA	J:43533
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:117608
Cellular Component	GO:0072687	meiotic spindle	IDA	J:228105
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912506
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0000795	synaptonemal complex	IDA	J:35110
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0051085	chaperone cofactor-dependent protein refolding	IBA	J:265628
Biological Process	GO:0007141	male meiosis I	IMP	J:44767
Biological Process	GO:0007140	male meiotic nuclear division	IMP	J:35110
Biological Process	GO:0090084	negative regulation of inclusion body assembly	ISO	J:164563
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	IMP	J:183833
Biological Process	GO:1901896	positive regulation of ATPase-coupled calcium transmembrane transporter activity	IMP	J:183833
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	IMP	J:77458
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IMP	J:77458
Biological Process	GO:0042026	protein refolding	ISO	J:164563
Biological Process	GO:0042026	protein refolding	IBA	J:265628
Biological Process	GO:0007286	spermatid development	IMP	J:35110
Biological Process	GO:0007283	spermatogenesis	IMP	J:228105
Biological Process	GO:0070194	synaptonemal complex disassembly	IMP	J:44767