Hspg2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Hspg2
perlecan (heparan sulfate proteoglycan 2)
MGI:96257

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0070052	collagen V binding	ISO	J:155856
Molecular Function	GO:0030021	extracellular matrix structural constituent conferring compression resistance	RCA	J:265607
Molecular Function	GO:0030021	extracellular matrix structural constituent conferring compression resistance	RCA	J:265604
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0002020	protease binding	IPI	J:206911
Molecular Function	GO:0005515	protein binding	IPI	J:206911
Molecular Function	GO:0005515	protein binding	IPI	J:79202
Molecular Function	GO:0005515	protein binding	IPI	J:110553
Cellular Component	GO:0005604	basement membrane	IBA	J:265628
Cellular Component	GO:0005604	basement membrane	IDA	J:139122
Cellular Component	GO:0005604	basement membrane	IDA	J:98778
Cellular Component	GO:0005604	basement membrane	IDA	J:98778
Cellular Component	GO:0005604	basement membrane	IDA	J:55507
Cellular Component	GO:0005604	basement membrane	IDA	J:98778
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:58700
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:81999
Cellular Component	GO:0005604	basement membrane	IDA	J:73993
Cellular Component	GO:0005604	basement membrane	IDA	J:55507
Cellular Component	GO:0005604	basement membrane	IDA	J:98778
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:27732
Cellular Component	GO:0005604	basement membrane	IDA	J:55507
Cellular Component	GO:0005604	basement membrane	IDA	J:95191
Cellular Component	GO:0005604	basement membrane	IDA	J:74542
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:155856
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:213088
Cellular Component	GO:0031012	extracellular matrix	IDA	J:95191
Cellular Component	GO:0031012	extracellular matrix	IDA	J:58700
Cellular Component	GO:0031012	extracellular matrix	IDA	J:110553
Cellular Component	GO:0031012	extracellular matrix	IDA	J:194150
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2426528
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-NUL-2426638
Cellular Component	GO:0005796	Golgi lumen	TAS	Reactome:R-MMU-2024090
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0007420	brain development	IMP	J:58700
Biological Process	GO:0048738	cardiac muscle tissue development	IMP	J:58700
Biological Process	GO:0048738	cardiac muscle tissue development	IMP	J:58700
Biological Process	GO:0048738	cardiac muscle tissue development	IMP	J:58700
Biological Process	GO:0048738	cardiac muscle tissue development	IMP	J:58700
Biological Process	GO:0048738	cardiac muscle tissue development	IMP	J:58700
Biological Process	GO:0060351	cartilage development involved in endochondral bone morphogenesis	IMP	J:67299
Biological Process	GO:0060351	cartilage development involved in endochondral bone morphogenesis	IMP	J:67299
Biological Process	GO:0002062	chondrocyte differentiation	IMP	J:67299
Biological Process	GO:0002062	chondrocyte differentiation	IMP	J:67299
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IMP	J:58700
Biological Process	GO:0001958	endochondral ossification	IMP	J:58700
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:58700
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:58700
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:58700
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:58700
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:58700
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:58700
Biological Process	GO:1905907	negative regulation of amyloid fibril formation	ISO	J:164563
Biological Process	GO:0007162	negative regulation of cell adhesion	ISO	J:155856
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:155856
Biological Process	GO:0008104	protein localization	IMP	J:74542
Biological Process	GO:0006898	receptor-mediated endocytosis	IGI	J:241063
Biological Process	GO:0006898	receptor-mediated endocytosis	IMP	J:241063
Biological Process	GO:0006898	receptor-mediated endocytosis	IGI	J:241063
Biological Process	GO:0007224	smoothened signaling pathway	ISO	J:155856

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24