GO Annotations Graph

• Symbol: Hyal1
• Name: hyaluronoglucosaminidase 1
• ID: MGI:96298

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0052757	chondroitin hydrolase activity	IMP	J:185446
Molecular Function	GO:0050501	hyaluronan synthase activity	ISO	J:164563
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	ISO	J:164563
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	IMP	J:239258
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016798	hydrolase activity, acting on glycosyl bonds	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0036117	hyaluranon cable	ISO	J:164563
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IMP	J:185446
Cellular Component	GO:0005764	lysosome	IDA	J:219474
Biological Process	GO:0005975	carbohydrate metabolic process	IEA	J:72247
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	ISO	J:164563
Biological Process	GO:0071347	cellular response to interleukin-1	ISO	J:164563
Biological Process	GO:0071467	cellular response to pH	ISO	J:164563
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	ISO	J:164563
Biological Process	GO:0071493	cellular response to UV-B	ISO	J:164563
Biological Process	GO:0030207	chondroitin sulfate catabolic process	IMP	J:185446
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	IMP	J:146040
Biological Process	GO:0030213	hyaluronan biosynthetic process	ISO	J:164563
Biological Process	GO:0030214	hyaluronan catabolic process	ISO	J:164563
Biological Process	GO:0030214	hyaluronan catabolic process	ISO	J:164563
Biological Process	GO:0030214	hyaluronan catabolic process	IBA	J:265628
Biological Process	GO:0030214	hyaluronan catabolic process	IMP	J:185446
Biological Process	GO:0030214	hyaluronan catabolic process	IMP	J:239258
Biological Process	GO:0030212	hyaluronan metabolic process	ISO	J:164563
Biological Process	GO:0006954	inflammatory response	ISO	J:164563
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0045785	positive regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0030307	positive regulation of cell growth	ISO	J:164563
Biological Process	GO:0010634	positive regulation of epithelial cell migration	ISO	J:164563
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	ISO	J:164563
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0045927	positive regulation of growth	ISO	J:164563
Biological Process	GO:1900106	positive regulation of hyaluranon cable assembly	ISO	J:164563
Biological Process	GO:0046677	response to antibiotic	ISO	J:164563
Biological Process	GO:0000302	response to reactive oxygen species	ISO	J:164563
Biological Process	GO:0009615	response to virus	IDA	J:182416
Biological Process	GO:0009615	response to virus	ISO	J:164563