GO Annotations Graph

• Symbol: Ica1
• Name: islet cell autoantigen 1
• ID: MGI:96391

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140090	membrane curvature sensor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:197677
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:65514
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	IBA	J:265628
Cellular Component	GO:0000139	Golgi membrane	ISO	J:155856
Cellular Component	GO:0000139	Golgi membrane	ISO	J:164563
Cellular Component	GO:0005795	Golgi stack	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0030667	secretory granule membrane	ISO	J:164563
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0030672	synaptic vesicle membrane	IDA	J:65514
Biological Process	GO:0006836	neurotransmitter transport	IEA	J:60000
Biological Process	GO:0050796	regulation of insulin secretion	IEA	J:72247
Biological Process	GO:0046928	regulation of neurotransmitter secretion	NAS	J:65514
Biological Process	GO:0043254	regulation of protein-containing complex assembly	ISO	J:155856
Biological Process	GO:0051049	regulation of transport	IBA	J:265628