Idua GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Idua
iduronidase, alpha-L
MGI:96418

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016798	hydrolase activity, acting on glycosyl bonds	IEA	J:60000
Molecular Function	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	IEA	J:72247
Molecular Function	GO:0003940	L-iduronidase activity	ISO	J:164563
Molecular Function	GO:0003940	L-iduronidase activity	ISO	J:155856
Molecular Function	GO:0003940	L-iduronidase activity	IBA	J:265628
Molecular Function	GO:0003940	L-iduronidase activity	IDA	J:21908
Molecular Function	GO:0003940	L-iduronidase activity	IMP	J:101932
Molecular Function	GO:0003940	L-iduronidase activity	IMP	J:155619
Molecular Function	GO:0003940	L-iduronidase activity	IMP	J:154691
Molecular Function	GO:0003940	L-iduronidase activity	IDA	J:155619
Molecular Function	GO:0003940	L-iduronidase activity	IMP	J:155619
Molecular Function	GO:0003940	L-iduronidase activity	IMP	J:177578
Molecular Function	GO:0003940	L-iduronidase activity	IDA	J:117749
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:155856
Cellular Component	GO:0030135	coated vesicle	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IDA	J:117749
Cellular Component	GO:0043202	lysosomal lumen	IMP	J:123676
Cellular Component	GO:0043202	lysosomal lumen	IMP	J:47999
Cellular Component	GO:0005764	lysosome	ISO	J:155856
Cellular Component	GO:0005764	lysosome	IMP	J:155619
Biological Process	GO:0008344	adult locomotory behavior	IMP	J:190495
Biological Process	GO:0007628	adult walking behavior	IMP	J:190495
Biological Process	GO:0060348	bone development	IMP	J:155619
Biological Process	GO:0060348	bone development	IMP	J:155619
Biological Process	GO:0005975	carbohydrate metabolic process	IEA	J:72247
Biological Process	GO:1990079	cartilage homeostasis	IMP	J:154691
Biological Process	GO:0000902	cell morphogenesis	IMP	J:39522
Biological Process	GO:0048878	chemical homeostasis	IMP	J:39522
Biological Process	GO:0030209	dermatan sulfate catabolic process	ISO	J:164563
Biological Process	GO:0030209	dermatan sulfate catabolic process	IMP	J:326249
Biological Process	GO:0030209	dermatan sulfate catabolic process	IMP	J:155619
Biological Process	GO:0030209	dermatan sulfate catabolic process	IMP	J:155619
Biological Process	GO:0030209	dermatan sulfate catabolic process	IMP	J:154691
Biological Process	GO:0030209	dermatan sulfate catabolic process	IDA	J:155619
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:220191
Biological Process	GO:0006027	glycosaminoglycan catabolic process	ISO	J:155856
Biological Process	GO:0006027	glycosaminoglycan catabolic process	IMP	J:154691
Biological Process	GO:0006027	glycosaminoglycan catabolic process	IMP	J:190495
Biological Process	GO:0006027	glycosaminoglycan catabolic process	IMP	J:190495
Biological Process	GO:0006027	glycosaminoglycan catabolic process	IMP	J:190495
Biological Process	GO:0006027	glycosaminoglycan catabolic process	IMP	J:155619
Biological Process	GO:0006027	glycosaminoglycan catabolic process	IMP	J:117749
Biological Process	GO:0006027	glycosaminoglycan catabolic process	IMP	J:177578
Biological Process	GO:0006027	glycosaminoglycan catabolic process	IDA	J:117749
Biological Process	GO:0030200	heparan sulfate proteoglycan catabolic process	IMP	J:101932
Biological Process	GO:0030200	heparan sulfate proteoglycan catabolic process	IMP	J:326249
Biological Process	GO:0030211	heparin catabolic process	IMP	J:155619
Biological Process	GO:0030211	heparin catabolic process	ISO	J:177578
Biological Process	GO:0030211	heparin catabolic process	IDA	J:155619
Biological Process	GO:0030211	heparin catabolic process	IMP	J:154691
Biological Process	GO:0030211	heparin catabolic process	IMP	J:177578
Biological Process	GO:0035108	limb morphogenesis	IMP	J:39522
Biological Process	GO:0007626	locomotory behavior	IMP	J:130215
Biological Process	GO:0007040	lysosome organization	IMP	J:155619
Biological Process	GO:0007040	lysosome organization	IMP	J:39522
Biological Process	GO:0007613	memory	IMP	J:130215
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0061037	negative regulation of cartilage development	IMP	J:154691
Biological Process	GO:0090341	negative regulation of secretion of lysosomal enzymes	IMP	J:117749
Biological Process	GO:0090341	negative regulation of secretion of lysosomal enzymes	IDA	J:117749
Biological Process	GO:0045780	positive regulation of bone resorption	IMP	J:154691
Biological Process	GO:0120158	positive regulation of collagen catabolic process	IMP	J:154691
Biological Process	GO:0048705	skeletal system morphogenesis	IMP	J:39522
Biological Process	GO:0008542	visual learning	IMP	J:130215

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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