Rbpj GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Rbpj
recombination signal binding protein for immunoglobulin kappa J region
MGI:96522

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:195490
Molecular Function	GO:0003682	chromatin binding	IDA	J:112960
Molecular Function	GO:0003682	chromatin binding	IDA	J:197142
Molecular Function	GO:0003682	chromatin binding	IDA	J:112960
Molecular Function	GO:0003677	DNA binding	ISO	J:74742
Molecular Function	GO:0003677	DNA binding	IDA	J:40289
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:83358
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:119151
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:139512
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:181926
Molecular Function	GO:0005515	protein binding	IPI	J:331358
Molecular Function	GO:0005515	protein binding	IPI	J:248235
Molecular Function	GO:0005515	protein binding	IPI	J:62777
Molecular Function	GO:0005515	protein binding	IPI	J:245357
Molecular Function	GO:0005515	protein binding	IPI	J:34426
Molecular Function	GO:0005515	protein binding	IPI	J:40289
Molecular Function	GO:0005515	protein binding	IPI	J:121427
Molecular Function	GO:0005515	protein binding	IPI	J:40289
Molecular Function	GO:0005515	protein binding	IPI	J:40289
Molecular Function	GO:0005515	protein binding	IPI	J:121406
Molecular Function	GO:0005515	protein binding	IPI	J:40289
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:123631
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:137568
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:123632
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:125691
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex	ISO	J:164563
Cellular Component	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-2976706
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-2976717
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-2976723
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4396387
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9016915
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9017420
Cellular Component	GO:0005634	nucleus	IDA	J:119151
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:74742
Cellular Component	GO:0005634	nucleus	IDA	J:114702
Cellular Component	GO:0005634	nucleus	IDA	J:39351
Cellular Component	GO:0005634	nucleus	IC	J:40289
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0032993	protein-DNA complex	ISO	J:155856
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:125691
Cellular Component	GO:0017053	transcription repressor complex	ISO	J:164563
Biological Process	GO:0001525	angiogenesis	IMP	J:93125
Biological Process	GO:0003176	aortic valve development	IMP	J:261826
Biological Process	GO:0060844	arterial endothelial cell fate commitment	IMP	J:93125
Biological Process	GO:0048844	artery morphogenesis	IMP	J:216917
Biological Process	GO:0036302	atrioventricular canal development	IMP	J:87765
Biological Process	GO:0009912	auditory receptor cell fate commitment	IMP	J:144981
Biological Process	GO:0030183	B cell differentiation	IMP	J:76240
Biological Process	GO:0097101	blood vessel endothelial cell fate specification	IGI	J:93125
Biological Process	GO:0072554	blood vessel lumenization	IMP	J:93125
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:93125
Biological Process	GO:0003214	cardiac left ventricle morphogenesis	IMP	J:187551
Biological Process	GO:0060379	cardiac muscle cell myoblast differentiation	IMP	J:178290
Biological Process	GO:0030154	cell differentiation	IMP	J:112960
Biological Process	GO:0045165	cell fate commitment	IMP	J:112960
Biological Process	GO:0008283	cell population proliferation	IGI	J:94813
Biological Process	GO:0008283	cell population proliferation	IGI	J:94813
Biological Process	GO:0008283	cell population proliferation	IMP	J:114702
Biological Process	GO:0060486	club cell differentiation	IMP	J:188519
Biological Process	GO:0060486	club cell differentiation	IMP	J:188519
Biological Process	GO:0042742	defense response to bacterium	IMP	J:76240
Biological Process	GO:0061371	determination of heart left/right asymmetry	TAS	J:93125
Biological Process	GO:0035912	dorsal aorta morphogenesis	IMP	J:93125
Biological Process	GO:0003157	endocardium development	IMP	J:119151
Biological Process	GO:0003160	endocardium morphogenesis	IMP	J:87765
Biological Process	GO:0009957	epidermal cell fate specification	IMP	J:114702
Biological Process	GO:0050673	epithelial cell proliferation	IGI	J:94813
Biological Process	GO:0050673	epithelial cell proliferation	IGI	J:94813
Biological Process	GO:0001837	epithelial to mesenchymal transition	IMP	J:87765
Biological Process	GO:0001837	epithelial to mesenchymal transition	IMP	J:87765
Biological Process	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	IMP	J:87765
Biological Process	GO:0048820	hair follicle maturation	IMP	J:114702
Biological Process	GO:0048820	hair follicle maturation	IMP	J:114702
Biological Process	GO:0007507	heart development	IMP	J:87765
Biological Process	GO:0001947	heart looping	TAS	J:93125
Biological Process	GO:0030097	hemopoiesis	IMP	J:97176
Biological Process	GO:0006959	humoral immune response	IMP	J:123631
Biological Process	GO:0002437	inflammatory response to antigenic stimulus	IMP	J:123631
Biological Process	GO:0032633	interleukin-4 production	IMP	J:123631
Biological Process	GO:0030216	keratinocyte differentiation	IMP	J:114702
Biological Process	GO:0060716	labyrinthine layer blood vessel development	IMP	J:93125
Biological Process	GO:0043011	myeloid dendritic cell differentiation	IMP	J:208234
Biological Process	GO:0045596	negative regulation of cell differentiation	IMP	J:57072
Biological Process	GO:0045596	negative regulation of cell differentiation	IMP	J:112960
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	IMP	J:226881
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:40289
Biological Process	GO:0030279	negative regulation of ossification	IMP	J:187551
Biological Process	GO:2000647	negative regulation of stem cell proliferation	IMP	J:114702
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:178290
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:119151
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:87765
Biological Process	GO:0030182	neuron differentiation	IMP	J:39351
Biological Process	GO:0061314	Notch signaling involved in heart development	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	IBA	J:265628
Biological Process	GO:0007219	Notch signaling pathway	IGI	J:217593
Biological Process	GO:0007219	Notch signaling pathway	IMP	J:87765
Biological Process	GO:0007219	Notch signaling pathway	IMP	J:144981
Biological Process	GO:0007219	Notch signaling pathway	IMP	J:217593
Biological Process	GO:0007219	Notch signaling pathway	IMP	J:146198
Biological Process	GO:0060853	Notch signaling pathway involved in arterial endothelial cell fate commitment	IC	J:93125
Biological Process	GO:0003151	outflow tract morphogenesis	IMP	J:87765
Biological Process	GO:0021983	pituitary gland development	IMP	J:112960
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	IMP	J:119151
Biological Process	GO:1901297	positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	IMP	J:186421
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IMP	J:119151
Biological Process	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis	IMP	J:119151
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:74742
Biological Process	GO:1901189	positive regulation of ephrin receptor signaling pathway	IMP	J:119151
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IGI	J:94813
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IGI	J:94813
Biological Process	GO:1901186	positive regulation of ERBB signaling pathway	IMP	J:119151
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:261826
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:261826
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:93125
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:216917
Biological Process	GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	TAS	J:93125
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:83358
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:119151
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:124179
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:165329
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:182392
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:87765
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:178290
Biological Process	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia	ISO	J:164563
Biological Process	GO:0007221	positive regulation of transcription of Notch receptor target	ISO	J:164563
Biological Process	GO:0007221	positive regulation of transcription of Notch receptor target	IGI	J:83687
Biological Process	GO:0003177	pulmonary valve development	IMP	J:261826
Biological Process	GO:0061344	regulation of cell adhesion involved in heart morphogenesis	IC	J:87765
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0050678	regulation of epithelial cell proliferation	IGI	J:217593
Biological Process	GO:0010468	regulation of gene expression	IMP	J:39351
Biological Process	GO:0010468	regulation of gene expression	IMP	J:39351
Biological Process	GO:2000241	regulation of reproductive process	IGI	J:217593
Biological Process	GO:0048505	regulation of timing of cell differentiation	IMP	J:112960
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:178290
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IGI	J:97176
Biological Process	GO:0048733	sebaceous gland development	IMP	J:114702
Biological Process	GO:0003139	secondary heart field specification	IGI	J:186421
Biological Process	GO:0003139	secondary heart field specification	IMP	J:186421
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:176833
Biological Process	GO:0001756	somitogenesis	TAS	J:93125
Biological Process	GO:0001756	somitogenesis	IMP	J:154114
Biological Process	GO:0072089	stem cell proliferation	IMP	J:114702
Biological Process	GO:0060412	ventricular septum morphogenesis	IMP	J:261826
Biological Process	GO:0003222	ventricular trabecula myocardium morphogenesis	IMP	J:119151

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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