Ihh GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ihh
Indian hedgehog
MGI:96533

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005113	patched binding	ISO	J:164563
Molecular Function	GO:0005113	patched binding	IPI	J:50930
Molecular Function	GO:0005113	patched binding	IBA	J:265628
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:53760
Molecular Function	GO:0005515	protein binding	IPI	J:226676
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0034189	very-low-density lipoprotein particle binding	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0031012	extracellular matrix	IDA	J:71184
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-8941290
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0045453	bone resorption	IDA	J:54678
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IMP	J:97179
Biological Process	GO:0043010	camera-type eye development	IMP	J:139168
Biological Process	GO:0060220	camera-type eye photoreceptor cell fate commitment	IMP	J:139168
Biological Process	GO:0051216	cartilage development	ISO	J:164563
Biological Process	GO:0051216	cartilage development	IMP	J:117221
Biological Process	GO:0001708	cell fate specification	IBA	J:265628
Biological Process	GO:0001708	cell fate specification	IMP	J:139168
Biological Process	GO:0048469	cell maturation	IMP	J:94274
Biological Process	GO:0008283	cell population proliferation	IMP	J:102948
Biological Process	GO:0008283	cell population proliferation	IMP	J:102948
Biological Process	GO:0007267	cell-cell signaling	IEA	J:72247
Biological Process	GO:0002062	chondrocyte differentiation	IMP	J:102948
Biological Process	GO:0002062	chondrocyte differentiation	IDA	J:99641
Biological Process	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	IMP	J:226676
Biological Process	GO:0035988	chondrocyte proliferation	IMP	J:171806
Biological Process	GO:0009790	embryo development	IMP	J:128367
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	IMP	J:139168
Biological Process	GO:0048557	embryonic digestive tract morphogenesis	IMP	J:62158
Biological Process	GO:0042733	embryonic digit morphogenesis	ISO	J:164563
Biological Process	GO:0042733	embryonic digit morphogenesis	IGI	J:163602
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:163602
Biological Process	GO:0009880	embryonic pattern specification	IMP	J:139168
Biological Process	GO:0072498	embryonic skeletal joint development	IMP	J:117221
Biological Process	GO:0060350	endochondral bone morphogenesis	IMP	J:59287
Biological Process	GO:0060350	endochondral bone morphogenesis	IMP	J:57297
Biological Process	GO:0003382	epithelial cell morphogenesis	IMP	J:139168
Biological Process	GO:0090136	epithelial cell-cell adhesion	IMP	J:139168
Biological Process	GO:0060323	head morphogenesis	IMP	J:171806
Biological Process	GO:0001947	heart looping	IMP	J:175111
Biological Process	GO:0001701	in utero embryonic development	IMP	J:128367
Biological Process	GO:0016539	intein-mediated protein splicing	IEA	J:72247
Biological Process	GO:0001763	morphogenesis of a branching structure	IMP	J:65293
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0035264	multicellular organism growth	IMP	J:62158
Biological Process	GO:0046639	negative regulation of alpha-beta T cell differentiation	IMP	J:145997
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0032331	negative regulation of chondrocyte differentiation	IMP	J:102948
Biological Process	GO:0048074	negative regulation of eye pigmentation	IMP	J:139268
Biological Process	GO:0033088	negative regulation of immature T cell proliferation in thymus	IMP	J:145997
Biological Process	GO:0033085	negative regulation of T cell differentiation in thymus	IMP	J:145997
Biological Process	GO:0048666	neuron development	IMP	J:62158
Biological Process	GO:0001503	ossification	IMP	J:73071
Biological Process	GO:0001649	osteoblast differentiation	IGI	J:226676
Biological Process	GO:0001649	osteoblast differentiation	IDA	J:226676
Biological Process	GO:0001649	osteoblast differentiation	IMP	J:88635
Biological Process	GO:0001649	osteoblast differentiation	IMP	J:226676
Biological Process	GO:0031016	pancreas development	IGI	J:65293
Biological Process	GO:0031016	pancreas development	IMP	J:62158
Biological Process	GO:0007389	pattern specification process	IMP	J:49653
Biological Process	GO:0007389	pattern specification process	IMP	J:49653
Biological Process	GO:0046638	positive regulation of alpha-beta T cell differentiation	IMP	J:145997
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:102948
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:117221
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGI	J:117221
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:139168
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	IDA	J:54678
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	ISO	J:155856
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IMP	J:139168
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	IMP	J:175111
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	ISO	J:164563
Biological Process	GO:0033089	positive regulation of T cell differentiation in thymus	IMP	J:145997
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:128367
Biological Process	GO:0016540	protein autoprocessing	IEA	J:72247
Biological Process	GO:0006029	proteoglycan metabolic process	IGI	J:171806
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0010468	regulation of gene expression	IBA	J:265628
Biological Process	GO:0040008	regulation of growth	IGI	J:157333
Biological Process	GO:0003406	retinal pigment epithelium development	IMP	J:139168
Biological Process	GO:0001501	skeletal system development	ISO	J:164563
Biological Process	GO:0001501	skeletal system development	IMP	J:102870
Biological Process	GO:0048745	smooth muscle tissue development	IMP	J:62158
Biological Process	GO:0007224	smoothened signaling pathway	ISO	J:164563
Biological Process	GO:0007224	smoothened signaling pathway	IBA	J:265628
Biological Process	GO:0007224	smoothened signaling pathway	IDA	J:226676
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:157333
Biological Process	GO:0061053	somite development	IMP	J:175111
Biological Process	GO:0001944	vasculature development	IMP	J:128367
Biological Process	GO:0030704	vitelline membrane formation	IMP	J:128367

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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