Il2ra GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Il2ra
interleukin 2 receptor, alpha chain
MGI:96549

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019976	interleukin-2 binding	IBA	J:265628
Molecular Function	GO:0019976	interleukin-2 binding	IPI	J:16175
Molecular Function	GO:0019976	interleukin-2 binding	IPI	J:16175
Molecular Function	GO:0004911	interleukin-2 receptor activity	ISO	J:164563
Molecular Function	GO:0004911	interleukin-2 receptor activity	ISO	J:164563
Molecular Function	GO:0004911	interleukin-2 receptor activity	ISO	J:155856
Molecular Function	GO:0004911	interleukin-2 receptor activity	IMP	J:64279
Molecular Function	GO:0005515	protein binding	IPI	J:168252
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:35057
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:113553
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:92334
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:172134
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:91939
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:53400
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:96628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:174697
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:98417
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:112602
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:61649
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:92679
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:99189
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:141227
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:137854
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:152384
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:118845
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:14194
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:64279
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:144049
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:16175
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:89706
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:34311
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:155686
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:17350
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:140498
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:89322
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:177992
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:139262
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:29796
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:141392
Cellular Component	GO:0016020	membrane	IEA	J:60000
Biological Process	GO:0050798	activated T cell proliferation	IMP	J:64279
Biological Process	GO:0006924	activation-induced cell death of T cells	IMP	J:64279
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IBA	J:265628
Biological Process	GO:0002437	inflammatory response to antigenic stimulus	ISO	J:155856
Biological Process	GO:0038110	interleukin-2-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0046651	lymphocyte proliferation	IMP	J:112602
Biological Process	GO:0046651	lymphocyte proliferation	IMP	J:112602
Biological Process	GO:0050728	negative regulation of inflammatory response	IMP	J:64279
Biological Process	GO:0050728	negative regulation of inflammatory response	IMP	J:84826
Biological Process	GO:0050672	negative regulation of lymphocyte proliferation	IMP	J:112602
Biological Process	GO:0042130	negative regulation of T cell proliferation	IMP	J:84826
Biological Process	GO:0007219	Notch signaling pathway	IGI	J:174697
Biological Process	GO:0042104	positive regulation of activated T cell proliferation	IMP	J:64279
Biological Process	GO:0045582	positive regulation of T cell differentiation	ISO	J:155856
Biological Process	GO:0042102	positive regulation of T cell proliferation	ISO	J:155856
Biological Process	GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation	IMP	J:112602
Biological Process	GO:0046013	regulation of T cell homeostatic proliferation	IMP	J:112602
Biological Process	GO:0002664	regulation of T cell tolerance induction	ISO	J:164563
Biological Process	GO:0043029	T cell homeostasis	IMP	J:84826

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24